論文 - 引間 知広
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Effect of diffusive direction across the skin on the penetration profile of chemicals in vitro 査読有り
Ryo MOROFUJI, Tomohiro HIKIMA, Kakuji TOJO
Biological & Pharmaceutical Bulletin 36 ( 11 ) 1760 - 1765 2013年11月
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経皮吸収に関する研究
引間知広
Cosme Tech Japan ( 株式会社じほう ) 2013年08月
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Prediction of percutaneous absorption in human of nicotine from marketed TTS using three-dimensional human cultured epidermis 査読有り
Tomohiro Hikima,Mayumi Komatsu,Daisuke Mori,Kakuji Tojo
Journal of Controlled Release 2013年06月
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Skin accumulation and penetration of a hydrophilic compound by a novel gemini surfactant, sodium dilauramidoglutamide lysine. 査読有り
Tomohiro HIKIMA, Yoshinaga TAMURA, Yukio YAMAWAKI, Masashi YAMAMOTO, Kakuji TOJO
International Journal of Pharmaceutics 443 ( 1-2 ) 288 - 292 2013年02月
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Prediction of percutaneous absorption in human using three-dimensional human cultureed epidermis LabCyte EPI-MODEL 査読有り
Tomohiro Hikima, Noriaki Kaneda, kyouhei Matsuo, Kakuji Tojo
Biological & Pharmaceutical Bulletin 35 ( 3 ) 362 - 368 2012年03月
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経皮治療システムにおける透過促進剤
引間知広,冨永健治
Cosmetic Stage ( 技術情報協会 ) ( 7 ) 10 - 13 2010年07月
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経皮治療システムにおける物理的透過促進法
引間知広,冨永健治
Cosmetic Stage ( 技術情報協会 ) ( 7 ) 14 - 18 2010年07月
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Mechanism of the synergistic skin penetration by sonophoresis and iontophoresis. 査読有り
Tomohiro Hikima,Shinya Ohsumi,Kenta Shirouzu,Kakuji Tojo
Biological & Pharmaceutical Bulletin 32 ( 5 ) 905 - 909 2009年05月
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Control of barrier capacity of stratum corneum by microdermabrasion. 査読有り
Kouhei Shirakami,Tomohiro Hikima,Kakuji Tojo
Journal of Chemical Engineering of Japan 41 ( 12 ) 1123 - 1126 2008年12月
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Synergistic effect of sonophoresis and iontophoresis in transdermal drug delivery 査読有り
Kenta Shirouzu,Tetsuya Nishiyama,Tomohiro Hikima,Kakuji Tojo
Journal of Chemical Engineering of Japan 42 ( 4 ) 300 - 305 2008年04月
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経皮治療システム用貼付剤製造装置の開発 招待有り 査読有り
引間知広,因昭一,中村昭範,東條角治
膜 32 ( 2 ) 116 - 119 2007年04月
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Bioequivalence of marketed transdermal delivery systems for tulobuterol 査読有り
Kakuji Tojo,Tomohiro Hikima
Biological & Pharmaceutical Bulletin 30 ( 8 ) 1576 - 1579 2007年04月
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Effect of molecular weight of penetrants on iontophortic transdermal delivery in vitro 査読有り
Takamitsu Miyagi,Tomohiro Hikima,Kakuji Tojo
American Institute of Chemical Engineers 2006年11月
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Skin enzymes distribution in transdermal drug delivery 査読有り
Tomohiro Hikima,Howard I. Maibach,Kakuji Tojo
American Institute of Chemical Engineers 2006年11月
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Gender differences of enzymatic activity and distribution of 17s-hydroxysteroid dehydrogenase in human skin in vitro 査読有り
Tomohiro Hikima,Howard I. Maibach
Skin Pharmacology and Physiology 20 ( 4 ) 168 - 174 2006年04月
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Effect of molecular weight of penetrants on iontophoretic transdermal delivery in vitro 査読有り
Takamitsu Miyagi,Tomohiro Hikima,Kakuji Tojo
Journal of Chemical Engineering of Japan 39 ( 3 ) 360 - 365 2006年04月
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Skin penetration flux and lag-time of steroids across hydrated and dehydrated human skin in vitro 査読有り
Tomohiro Hikima,Howard I. Maibach
Biological & Pharmaceutical Bulltein 29 ( 11 ) 2270 - 2273 2006年04月
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Effect of molecular weight of FITC-dextrans on iontophoretic transdermaldelivery in vitro 査読有り
Takamitsu Miyagi,Tomohiro Hikima,Kakuji Tojo
The aaps Journal (AAPS Natonal Biotechnology Conference) 7 ( S1 ) 2005年06月
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Age and gender differences of enzymes distrbution and activity in human skin 査読有り
Tomohiro Hikima,Howard I.Maibach,KakujiTojo
The AAPS Journal (AAPS National Biotechnoligy Conference) 7 ( S1 ) 2005年06月
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Skin metabolism in transdermal therapeutic systems
Tomohiro Hikima, Kakuji Tojo, and Howard I. Maibach
Skin Pharmacology and Physiology ( Karger Publishers ) 18 ( 4 ) 153 - 159 2005年04月