研究者詳細 - 山田　宏

論文 - 山田　宏

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Stress evaluation along the posterior annular circumferential tears on the L5-S1 spinal unit as an index of tear progression 査読有り国際誌

Vinyas, Bhat, S.K., Yamada, H., Kumar, N., Adhikari, R., Bhat N, S.

Journal of Orthopaedics 67 148 - 164 2025年09月

Deformation analysis of forearm soft tissues surrounding the cephalic vein under shear on the skin surface using ultrasound video images 査読有り国際誌

H. Yamada, Y. Tanoue, S. Shimoide, M. Tanaka

Mechanical Engineering Journal 11 ( 6 ) 24-00191 2024年12月

Radial force and wire structure determine the onset of covered self-expandable metal stent migration in endoscopic ultrasound-guided hepaticogastrostomy: Measurement of sliding-resistance force using a porcine model 査読有り国際誌

T. Koga, H. Yamada, Y. Ishida, N. Tsuchiya, T. Kitaguchi, K. Matsumoto, M. Fukuyama, N. Kojima, F. Hirai

Journal of Hepato-Biliary-Pancreatic Sciences 31 ( 11 ) 840 - 849 2024年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

Background: Self-expandable metal stent (SEMS) migration after endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is a severe complication. The migration risk could be related to the surface friction of SEMS, assumed to be affected by the wire structure and mechanical properties, including radial force (RF); however, their relevance remains unclear. This experimental study aimed to assess the mechanical properties of SEMS involved in the onset of stent migration by measuring the sliding-resistance force (SF) as the SEMS moves through the stomach wall. Methods: The SF of seven types of 8-mm diameter SEMS (four braided and three laser-cut types) and porcine stomach wall was measured with a universal testing machine. The SF of each SEMS was measured three times, and the average maximum SF (SFmax) was used for analysis. The correlation between SFmax and RF of each SEMS was evaluated. Results: SFmax and RF showed a very strong positive correlation (r = 0.92). Compared to the regression line predictions in the scatter plots of SFmax and RF, the SFmax of laser-cut and braided type SEMSs had positive and negative residuals, respectively. Conclusions: Selecting a laser-cut type SEMS with a higher RF may more effectively prevent the onset of stent migration against the stomach wall in EUS-HGS.

DOI： 10.1002/jhbp.12050

Scopus

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In-silico study on cumulative effects of degeneration and circumferential annular tear on the L5-S1 spinal unit 査読有り国際誌

Vinyas, S.K. Bhat, H. Yamada, S.N. Bhat

Biomedical Physics & Engineering Express 10 ( 6 ) 065009 2024年09月

記述言語：英語掲載種別：研究論文（学術雑誌）

Low back pain is a serious health concern prevalent in majority of the people around the world, especially in case of the elderly. The root cause for this is mostly observed to be the development of lesions/ tears complemented by degenerative effects in the intervertebral disc of L4-L5 and L5-S1 segments. This study aims to analyse the effects of disc degeneration and tears on the mechanical responses of the L5-S1 spinal unit, which has not been investigated. The annulus is represented by an anisotropic hyperelastic Gasser-Ogden-Holzapfel (GOH) model wherein the effect of degeneration is defined by varying the constants responsible for the behaviour of the material in different strain-ranges. A systematic approach is proposed for modelling the effects of disc degeneration in the annulus. Further, the commonly found anterior circumferential tear is modelled to understand its combined effects with degeneration of the annulus. The damaging effect of the tear was limited only to extension movement, causing critical stress variations in its vicinity. However, degeneration had a significant influence on both stress and range of motion of the spinal unit across all types of movements. This study highlights the complex relationship of the physiological movements with pathogenesis of tear and degeneration leading to discogenic pain thus enabling clinicians to develop conservative treatment strategies for specific age groups.

DOI： 10.1088/2057-1976/ad7608

Scopus

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生体軟組織の非線形な応力－ひずみ関係式と初期弾性率招待有り

山田　宏

機械の研究 ( 養賢堂 ) 76 ( 4 ) 247 - 257 2024年04月

Mechanical characterization of dissected and dilated human ascending aorta using Fung-type hyperelastic models with pre-identified initial tangent moduli for low-stress distensibility 査読有り国際誌

Bhat S.K., Yamada H.

Journal of the Mechanical Behavior of Biomedical Materials ( Elsevier BV ) 125 104959 2022年01月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Ascending aortic dissection (AD) is a potentially fatal vascular disease associated with degradation and fragmentation of the elastic fibers in the aortic media, increasing low-stress distensibility, and a dilated aorta may lead to dissection. In this study, a Fung-type hyperelastic model was formulated incorporating the initial tangent moduli (ITM) of stress–strain curves as an index of low-stress distensibility. ITM were correlated with the material constants by linearizing incompressible stress–strain relationships at zero strain. For uniaxial loading tests, the robustness of the material constants was examined in the stress ranges of 0–200, 0–180, and 0–160 kPa and to the ITM values of 100%, 95%, and 90%. Examination revealed stable changes in the material constants of 80% of the specimens. For equibiaxial stretch tests, the material constants were determined for each curve of the isotropic and anisotropic deformation groups by pre-identifying the ITM and minimizing fitting errors using isotropic or anisotropic models. The errors for all groups were <6% using a transversely isotropic model, and <10% for an orthotropic model. Comparisons with experimental curves showed that Fung-type models described both the ITM and significant stiffening at high stress levels. The mechanical characteristics of the aorta in the stage prior/posterior to dissection is such that while hardening occurs under both low- and high-stress levels with an increase in collagen content as an aging response, softening occurs under low-stress conditions due to histological abnormalities such as elastin deficiency and fragmentation. Numerical simulations using Fung-type models implied that elastic fiber degeneration and fragmentation in AD tissues reduced not only the low-stress stiffness but also the elastic stiffness with superimposed shear. The latter stiffness was modulated by the stiffening at high stress levels in tensile deformation behavior and normal-strain state under physiological loading conditions, and therefore provides further insight into wall rupture.

DOI： 10.1016/j.jmbbm.2021.104959

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褥瘡の発症・予防に関わる力学的因子の評価招待有り

山田宏

非破壊検査 70 ( 4 ) 158 - 164 2021年04月

Measurement and finite element analysis of the load-dependent pressure redistribution behavior of various types of mattresses 査読有り

Fuwa Y., Hasan W.Z.W., Yamada H.

Journal of Mechanics in Medicine and Biology 20 ( 5 ) 2020年06月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Load dependence must be kept in mind when evaluating mattress pressure redistribution, to prevent the development of pressure ulcers at bony prominences. However, there is no standardized method for analyzing load-dependent behavior after mattress pressure redistribution. In this study, a portable palmtop device with a simple load-sensing mechanism was developed for measuring the mean pressure exerted by a protruding shaft surrounded by a disc on low-resilience polyurethane (LRPu) foam, latex foam, coconut fiber and latex (CFL) mattresses, as well as polyurethane (Pu) foam bed and an LRPu foam mattress laid on a bed. Finite element (FE) analysis was used to analyze deformation and contact pressure in detail. The pressure redistribution was greatest for the LRPu foam mattress, and excessive compression was avoided by using an underlay made of stiff Pu foam. FE analysis revealed that the contact pressure increased significantly near the outer circumference of the protruding shaft and the surrounding disc. Significant nonuniformity in pressure was evident, according to the edge and bottom geometry of the device. The measurements and FE analysis revealed load-dependent pressure redistribution behavior, which should allow mattresses to be tailored on an individual basis.

DOI： 10.1142/S0219519420500311

Kyutacar

Scopus

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Identification of uniaxial deformation behavior and its initial tangent modulus for atheromatous intima in the human carotid artery and thoracic aorta using three-parameter isotropic hyperelastic models 査読有り

Bhat S.K., Sakata N., Yamada H.

Journal of Mechanics in Medicine and Biology 20 ( 3 ) 2020年05月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

© 2020 World Scientific Publishing Company. Uniaxial stretching tests are used for mechanical identification of small fibrous regions of atheromatous arteries. Material constants in isotropic hyperelastic models are determined to minimize the fitting error for the stress-strain curve. We developed a novel method to better characterize the material constants in typical forms of Yeoh, Ogden, Chuong-Fung (CF) and Gasser-Ogden-Holzapfel (GOH) isotropic hyperelastic models for fibrous caps and normal intimal layers from human carotid artery and thoracic aorta by incorporating Young's modulus, i.e., the initial tangent modulus of uniaxial stress-strain relationships, as one of three material constants. We derived a unified, isotropic form for the anisotropic exponential-Type strain energy density functions of CF and GOH models. The uniaxial stress-strain relationship equations were expanded to Maclaurin series to identify Young's modulus as a coefficient of the linear term of the strain and to examine the roles of the material constants in the nonlinear function. The remaining two material constants were determined by curvefitting. The incorporation of Young's modulus into the CF and GOH models gave reasonable curvefitting, with errors <10%, whereas large errors (>10%) were observed in one case for the Yeoh model and in two cases for the Ogden model.

DOI： 10.1142/S0219519420500141

Kyutacar

Scopus

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High Salt intake worsens aortic dissection in mice: Involvement of IL (Interleukin)-17A-dependent ECM (extracellular matrix) metabolism 査読有り

N. Nishida, H. Aoki, S. Ohno-Urabe, M. Nishihara, A. Furusho, S. Hirakata, M. Hayashi, S. Ito, H. Yamada, Y. Hirata, H. Yasukawa, T. Imaizumi, H. Tanaka, Y. Fukumoto

Arteriosclerosis, Thrombosis, and Vascular Biology 40 ( 1 ) 189 - 205 2020年01月

記述言語：英語掲載種別：研究論文（学術雑誌）

OBJECTIVE: Aortic dissection (AD) is a fatal disease that occurs suddenly without preceding clinical signs or symptoms. Although high salt intake is a proposed risk factor for cardiovascular diseases, the relationship between AD and high salt intake has not been clarified. We examined the effect of high-salt challenge on a mouse AD model. Approach and Results: AD was induced in male mice by continuous infusion of β-aminopropionitrile and Ang II (angiotensin II). High-salt challenge exacerbated aortic wall destruction in AD. Deletion of Il17a (IL-17KO [IL (interleukin)-17A knockout]) did not affect the AD phenotype at baseline, but it abolished the high salt-induced worsening of the aortic destruction. Unexpectedly, aortas of IL-17KO mice exhibited global changes in ECM (extracellular matrix)-related genes without alteration of proinflammatory genes, altered architecture of collagen fibers, and reduced stiffness before AD induction. The aortas of IL-17KO mice were less sensitive to AD-inducing stimuli, as shown by the induction of phenotypic modulation markers SMemb and vimentin, suggesting a reduced stress response. The aortas of IL-17KO mice had a higher population of smooth muscle cells with nuclear-localized phosphorylated Smad2, indicative of TGFβ (transforming growth factor-beta) signal activation. Consistently, pretreatment of smooth muscle cells in culture with IL-17A blunted the activation of Smad2 by TGFβ1. CONCLUSIONS: These findings indicate that high salt intake has a worsening effect on AD in the context of high aortic wall stiffness, which is under the control of IL-17A through ECM metabolism. Therefore, salt restriction may represent a low-cost and practical way to reduce AD risk.

DOI： 10.1161/ATVBAHA.119.313336

Scopus

PubMed

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Finite element modelling of a bulging behavior in a cerebral artery with dissection 査読有り国際誌

S. K. Bhat, H. Yamada, N. Sakata

CMBE19 Proceedings, 6th International Conference on Computational & Mathematical Biomedical Engineering 838 - 841 2019年06月

Application of finite element analysis on balloon expandable coronary stents: A review

Bekal C., Yamada H., Shetty R., Shenoy S.

International Journal of Engineering and Technology(UAE) ( Science Publishing Corporation Inc ) 7 ( 3 ) 1640 - 1647 2018年08月

記述言語：英語掲載種別：記事・総説・解説・論説等（学術雑誌）

© 2018 Chandrakantha Bekal et. al. Numerical analysis of complex physical environment continues to be preferred over "build and test" approach in product development process. Finite Element Analysis (FEA) of coronary artery stenting is studied and researched worldwide for many years. Potential of using FEA for mimicking in-vivo is high as experimental test is ruled out for variety of reasons. This review aims at discussing issues and challenges of numerical simulation based on part of available literature on usage of FEA techniques for investigating behavior of balloon expandable (BE) coronary stents inside artery. Literatures of past 16 years of study on the structural analysis is summarized and potential issues for research is discussed. Study tries to investigate deployment characteristics and biomechanical response of artery post stenting and significance of non-physiological conditions induced. Effects of geometrical parameters, simulation strategies are summarized. Study mainly underscores the potential challenges of reliable numerical investigation. Scope of FEA in predicting contributor for in-stent reste-nosis (ISR), a major drawback of stenting procedure, by correlating the engineering aspect of stent design and its clinical significance supported by clinical trials are highlighted. Study is expected to serve as qualitative assessment for cardiologists to minimize procedural failure and quantitative tool for the designers for stent optimization.

DOI： 10.14419/ijet.v7i3.13845

Scopus

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Finite element analysis of a rupture-induced deformation of a carotid atherosclerotic plaque with intraplaque hemorrhage 査読有り

ESMAEILI MONIR Hamed, SENJU Omi, OGATA Toshiyasu, INOUE Tooru, SAKATA Noriyuki, YAMADA Hiroshi

Journal of Biomechanical Science and Engineering 13 ( 1 ) 17-00436 2018年03月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

<p>Intraplaque hemorrhage (IPH), bleeding in a plaque, is caused by a neocapillary rupture in an atherosclerotic plaque. We used contrast-enhanced ultrasonography to diagnose carotid atherosclerotic plaques before carotid endarterectomy (CEA), a surgical operation to remove an arterial intimal layer including a plaque lesion. We found lumenward (inward) deformation in some cases of ruptured plaques with IPH. The aim of this study was to evaluate the mechanical effects of infiltrated blood in the lipid core on the luminal shape of the ruptured plaque in the short-axis view. We created a finite element model of a carotid artery bifurcation with a ruptured plaque based on a sample obtained from CEA. As physiological loads, we assigned pressures on the surfaces of the lumen and the lipid core, the sum of a gradual pressure drop in the artery obtained from computational fluid dynamics analysis and a uniform pressure, and a constant longitudinal stretch. In the simulation, the fibrous cap in the ruptured model became almost flat in the short-axis view with lumenward deformation, being less deformed than that observed in ultrasonography. The simulation results show that inward deformation of the fibrous cap is correlated with an equal pressure in the lumen and the lipid core. In comparison, a hyperelastic model of soft unruptured plaque reproduced a round lumen. A better understanding of contrast-enhanced ultrasonography images from a mechanical perspective may facilitate the morphological identification of plaque rupture with IPH.</p>

DOI： 10.1299/jbse.17-00436

Scopus

CiNii Article

その他リンク： https://ci.nii.ac.jp/naid/130006247203

Skin stiffness determined from occlusion of a horizontally running microvessel in response to skin surface pressure: a finite element study of sacral pressure ulcers 査読有り

H. Yamada, Y. Inoue, Y. Shimokawa, K. Sakata

Medical & Biological Engineering & Computing 55 ( 1 ) 79 - 88 2017年01月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）

Pressure ulcers occur following sustained occlusion of microvessels at bony prominences under skin surface pressure (SSP). However, the mechanical conditions of the surrounding soft tissue leading to microvascular occlusion are not fully understood. This study determined the stiffness of homogenized skin with microvasculature at the sacrum that occludes microvessels at an SSP of 10 kPa (consistent with a standard mattress) and recovers from occlusion at 5 kPa (consistent with a pressure-redistribution mattress). We conducted two-dimensional finite element analyses under plane stress and plane strain conditions to determine the stiffness of the skin. The results for plane stress conditions show that the microvessel was occluded with a Young’s modulus of 23 kPa in response to an SSP of 10 kPa at the center of the sacrum and that the circulation recovered following a reduction in the SSP to 5 kPa. The resulting Young’s modulus is consistent with reported data. Our study indicates that the critical value of the SSP for microvascular occlusion is determined not only by the stiffness of homogenized skin with microvasculature but also by the intraluminal pressure, microvascular wall stiffness, and body support conditions.

DOI： 10.1007/s11517-016-1500-2

Scopus

PubMed

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Assessment of the relationship between deformation characteristics and the presence of calcification in human atheromatous plaques using uniaxial stretching evaluations with digital image correlation, CT scanning and histological examination 査読有り

H. Esmaeili Monir, H. Yamada, N. Sakata, Y. Morita, Y. Nakashima

Journal of Biomechanical Science and Engineering 11 ( 3 ) 15-00611 2016年09月

Finite element modelling of the common carotid artery in the elderly with physiological intimal thickening using layer-specific stress-released geometries and nonlinear elastic properties 査読有り国際誌

H. Esmaeili Monir, H. Yamada, N. Sakata

Computer Methods in Biomechanics and Biomedical Engineering 19 ( 12 ) 1286 - 1296 2016年09月

力学試験と超弾性モデルの適用によるウレタンフォームマットレスの骨突起部圧分散メカニズムの解明査読有り

井上仁瑛，山田宏

バイオメカニズム 23 233 - 242 2016年07月

Age-related distensibility and histology of the ascending aorta in elderly patients with acute aortic dissection 査読有り

H. Yamada,N. Sakata,H. Wada,T. Tashiro,E. Tayama

Journal of Biomechanics 48 ( 12 ) 3267 - 3273 2015年09月

A nonlinear finite element simulation of balloon expandable stent for assessment of plaque vulnerability inside a stenotic artery（共著）査読有り

A. Karimi, M. Navidbakhsh, H. Yamada, R. Razaghi

Medical & Biological Engineering & Computing 52 ( 7 ) 589 - 599 2014年07月

Reconstruction of small diameter arteries using decellularized vascular scaffolds（共著）査読有り

Y. Nagaoka, H. Yamada, T. Kimura, A. Kishida, T. Fujisato, K. Takakuda

Journal of Medical and Dental Sciences 61 ( 1 ) 33 - 40 2014年03月

Low pressure condition of a lipid core in an eccentrically developed carotid atheromatous plaque: A static finite element analysis（共著）査読有り

H. Yamada,N. Sakata

Journal of Biorheology 27 ( 1 ) 9 - 17 2013年11月

基質伸展下の内皮細胞底面における変位場の微視的解析（共著）査読有り

高嶋一登, 山田　宏

日本バイオレオロジー学会誌 26 ( 3 ) 109 - 112 2012年10月

Abaqusによる血管・細胞の変形挙動解析

山田宏

バイオメカニズム学会誌 ( バイオメカニズム学会 ) 34 ( 2 ) 157 - 163 2010年05月

Correlation between stress/strain and the retention of lipoproteins and rupture in atheromatous plaque of the human carotid artery: A finite element study（共著）査読有り

H. Yamada,K. Yuri,N. Sakata

Journal of Biomechanical Science and Engineering 5 ( 4 ) 291 - 302 2010年05月

Three-dimensional morphometry of single endothelial cells with substrate stretching and image-based finite element modeling 査読有り

H. Yamada,N. Mouri,S. Nobuhara

EURASIP Journal on Advances in Signal Processing 2010 2009年11月

Finite element models with dense focal adhesions reproduce the deformation of an endothelial cell under substrate stretching 査読有り

山田　宏

Proceedings of the 4th Asian Pacific Conference on Biomechanics 279 - 280 2009年04月

The effect of temperature on the morphology of fibroblasts in a collagen gel in nutrient-free medium 査読有り

H. Yamada,S. Nobuhara,S. Miyata

Proceedings of the 5th International Conference on Information Technology and Applications in Biomedicine 539 - 540 2008年05月

Hardening of the porcine thoracic aorta subjected to freezing and thawing: Experimental evaluation and mathematical modeling 査読有り

H. Yamada,K. Yasuno,K. Fujisaki,H. Ishiguro

Proceedings of the First ASME Micro/Nanoscale Heat Transfer International Conference 2008年01月

Orientation of apical and basal actin stress fibers in isolated and subconfluent endothelial cells as an early response to cyclic stretching 査読有り

H. Yamada,H. Ando

Molecular & Cellular Biomechanics 4 ( 1 ) 1 - 12 2007年03月

A simple method of estimating the stress acting on a bilaterally symmetric abdominal aortic aneurysm 査読有り

H. Yamada,Y. Hasegawa

Computer Methods in Biomechanics and Biomedical Engineering 10 ( 1 ) 53 - 61 2007年02月

Three-dimensional finite element modeling of a vascular endothelial cell based on confocal microscopic images at unstretched and stretched states 査読有り

H. Yamada,Y. Takahashi

Proceedings of the Second Asian Pacific Conference on Biomechanics 2005年11月

Effects of actin binding and substrate deformation on the array of actin filaments in an endothelial cell under cyclic stretch: Numerical simulation study 査読有り国際誌

H. Yamada, H. Ando

Proceedings of the 2005 Summer Bioengineering Conference 653 - 654 2005年06月

Evaluation of possible stress distributions in abdominal aorta on the basis of physiologically loading data 査読有り

H. Yamada,S. Momii

Proceedings of the 2004 ASME International Mechanical Engineering Congress and Exposition 2 1 - 2 2004年11月

血管内皮細胞の変形とストレスファイバーの配向に関する数値解析査読有り

山田宏,松村仁，森田大作

バイオメカニズム 17 2004年08月

培養血管内皮細胞の基質伸展下での力学的挙動に対する有限要素解析査読有り

山田宏，松村仁

日本機械学会論文集Ａ編 70 ( 693 ) 2004年05月

Geometry-dependent deformations of the vascular endothelial cell: Investigation of intracellular behavior with finite element analysis 査読有り

H. Yamada,D. Kageyama

Proceedings of the First Asian Pacific Conference on Biomechanics 2004年03月

Modeling and numerical simulation of the mechanical responses in vascular endothelial cells 査読有り

H. Yamada,J. Matsumura,D. Kageyama

Proceedings of the Workshop on Biomechanical Engineering and Biomaterials - The International Symposium on Bio-Inspired Systems 2004年01月

Orientation of Stress Fibers in a Cultured Endothelial Cell under Cyclic Deformation Taking Account of its Nonuniform Deformatin: Strain Limit Hypothesis and Numerical Simulations 査読有り

H. Yamada,D. Morita,J. Matsumura

Proc.2003 Summer Bioengineering Conference 41 - 42 2003年04月

Finite Element Analysis of Cultured Endothelial Cell under Uniaxial Stretch : Effect of Cell Shape on strain Distribution 査読有り

H. Yamada,J. Matsumura,D. Kageyama

Proc. 2003 Summer Bioenginnring Conference 1029 - 1030 2003年04月

Numerical Simulation of Stress Fiber Orientation in Cultured Endothelial Cells under Biaxial Cyclic Deformation Using the Strain Limit Hypothesis 査読有り

H. Yamada,D. Morita,J. Matsumura,T. Takemasa,T. Yamaguchi

JSME International Journal, Series C 45 ( 4 ) 880 - 888 2002年12月

Substrate Deformation Governs the Orientation of Stress Fibers in Cultured Cells under Cyclic Deformation: A Hypothesis and Theoretical Predictions 査読有り

Hiroshi YAMADA,T. Takemasa,T. Yamaguchi

Proc. 18th Congress of the International Society of Biomechanics 2001年07月

患者起立介助の模擬作業実験に基づく介助作業能力の力学的評価査読有り

山田宏,小野雄一郎,蛭田秀一,島岡みどり,堀文子,安藤詳子,服部洋兒,今枝敏彦

ライフサポート 12 ( 4 ) 125 - 130 2000年12月

骨の力学的再構築過程に対する数理モデルの定式化査読有り

田中英一，山本創太，青木洋一，岡田崇洋，山田宏

日本機械学会論文集A編 66 ( 641 ) 191 - 197 2000年04月

Theoretical Study of Intracellular Stress Fiber Orientation under Cyclic Deformation 査読有り

H. Yamada,T. Takemasa,T. Yamaguchi

Journal of Biomechanics 33 ( 11 ) 1501 - 1505 2000年04月

Relationship between Orientation Angle in Intracellular Stress Fibers and Range of Uniaxial Cyclic Stretch 査読有り

H. Yamada,T. Takemasa,T. Yamaguchi

2000 Advances in Bioengineering BED-48 81 - 82 2000年04月

Mechanically Optimized Orientation of Intracellular Stress Fibers under Cyclic Stretch 査読有り

H. Yamada,T. Takemasa,T. Yamaguchi

Proceedings of the ASME Heat Transfer Division HTD-366 ( 2 ) 127 - 132 2000年04月

上肢作業における筋負担に関する生理学的検討-近赤外線分光法による僧坊筋領域の血流動態の測定-

小野雄一郎,今枝敏彦,栗田秀樹,巽あさみ,山本恵申,蛭田秀一,島岡みどり,安藤詳子,堀文子,服部洋兒,山田宏,吉田勉,谷脇弘茂,長岡芳

総合保健体育科学 23 ( 1 ) 33 - 38 2000年04月

介護に関わる労働衛生の動向と課題

小野雄一郎,今枝敏彦,安藤詳子,堀文子,巽あさみ,蛭田秀一,島岡みどり,服部洋兒,山田宏,吉田勉,谷脇弘茂,長岡芳,栗田秀樹

総合保健体育科学 23 ( 1 ) 55 - 61 2000年04月

ベッドから車椅子への移動介助に関する実験的検討-介助者と患者役の自覚的評価-

山田　宏

総合保健体育科学 23 ( 1 ) 39 - 42 2000年04月

Finite Element Modeling and Numerical Simulation of the Artery in Active State 査読有り

H. Yamada,T. Shinoda,E. Tanaka,S. Yamamoto

JSME Int. J., Series C 42 ( 3 ) 501 - 507 1999年04月

A Mathematical Model of Arteries in the Active State (Incorporation of Active Stress and Activation Parameter) 査読有り

山田　宏

JSME Int. J., Series C 42 ( 3 ) 545 - 551 1999年04月

A Mathematical Model of Skeletal Muscle and Numerical Simulations of Its Response Under Stretching 査読有り

H. Yamada,J. Kajzer

JSME Int. J., Series C 42 ( 3 ) 508 - 513 1999年04月

A Mathematical Model of Bone Remodeling Taking Account of Bone Resorption under Overload 査読有り

E. Tanaka,S. Yamamoto,Y. Aoki,T. Okada,H. Yamada

Proc. 1999 Bioeng. Conf., ed. by V. K. Goel, R. L. Spilker, G. A. Ateshian and L. J. Solowsky BED-42 575 - 576 1999年04月

Numerical Simulations of Mechanical Behavior of Artery Taking Account of Dose Dependence of Activation 査読有り

H. Yamada,T. Shinoda,E. Tanaka,S. Yamamoto

Proc. 1999 Bioeng. Conf., ed. by V. K. Goel, R. L. Spilker, G. A. Ateshian and L. J. Solowsky BED-42 243 - 244 1999年04月

重量挙上作業における生体反応と体力との関係

蛭田秀一,島岡みどり,小野雄一郎,堀文子,安藤詳子,山田宏,巽あさみ,服部洋兒,今枝敏彦

総合保健体育科学 22 ( 1 ) 63 - 67 1999年04月

社会福祉施設職員の頸肩腕痛および腰痛の有訴率

小野雄一郎,島岡みどり,蛭田秀一,今枝敏彦,安藤詳子,堀文子,巽あさみ,山田宏,島正吾,吉田勉,谷脇弘茂,長岡芳,栗田秀樹

総合保健体育科学 22 ( 1 ) 69 - 79 1999年04月

A Constitutive Model to Describe Bone Remodeling Process 査読有り

E. Tanaka,S. Yamamoto,Y. Aoki,T. Okada,H. Yamada

Proc. The Fifth Japan-USA-Singapore-China Conf. on Biomechanics 160 - 161 1998年04月

A Mathematical Model of the Artery Focused on the Behavior of Smooth Muscles in Active State 査読有り

H. Yamada,T. Shinoda,E. Tanaka,S. Yamamoto

1998 Advances in Bioengineering, ASME BED-39 61 - 62 1998年04月

An Activation Model by a Neural Stimulation under Transient Stretching with an Application to Yielding 査読有り

H. Yamada,H. Takeuchi,J. Kajzer,K. Nishio

Proc. The Fifth Japan-USA-Singapore-China Conf. on Biomechanics 118 - 119 1998年04月

The Effects of Left Ventricular Strestch vursus Cavity Pressure on Intramyocardial Pressure 査読有り

F.C.P. Yin,H. Yamada

Cardiovascular Reseach 34 299 - 305 1997年04月

平滑筋活性状態での動脈壁の力学的挙動のモデル化(能動的応力と活性化パラメータの導入) 査読有り

山田　宏

日本機械学会論文集A編 63 ( 614 ) 2257 - 2262 1997年04月

A Constitutive Model of Mechanical Bone Remodeling by Using Internal State Variable Theory 査読有り

E. Tanaka,H. Yamada,S. Yamamoto

Proc. Third Int. Sym. Microstructures and Mech. Properties of New Eng. Materials 637 - 642 1997年04月

Mechanical Effects of Smooth Muscle Activation on the Vascular Wall 査読有り

H. Yamada,S. Yamamoto,E. Tanaka

Proc. Third Int. Sym. Microstructures and Mech. Properties of New Eng. Materials 643 - 648 1997年04月

Three-Dimensional Deformation Analyses of a Local Region of the Left Ventricular Wall with Tagged MR Images 査読有り

H. Yamada,C. Wang,K. Sekioka

Proc. Int. Conf. New Frontiers in Biomech. Eng. 327 - 330 1997年04月

A Mechanical Model and Stress Analysis of Arteries in Active State 査読有り

山田　宏

Proc. 1997 Bioengineering Conference 467 - 468 1997年04月

イヌ冠動脈の流動抵抗に対する周辺組織と心筋組織の力学的影響査読有り

山田宏,P. Sipkema,F.C.P. Yin

日本機械学会論文集A編 62 ( 604 ) 2838 - 2845 1996年04月

ウサギ左心室壁の心筋内圧力の測定査読有り

山田宏,F. Yin

材料 45 ( 2 ) 235 - 240 1996年04月

Coronary Artery Resistance Changes Depend on How Surrounding Myocardial Tissue is Stretched 査読有り

P. Sipkema,H. Yamada,F.C.P. Yin

Am.J.Physiol 270 H924 - H934 1996年04月

Effects of Stretching Surrounding Tissues on Hydraulic Resistance of a Blood Vessels-A Finite Element Analysis 査読有り

H. Yamada,F.C.P. Yin,P. Sipkema

Proc. 4th China-Japan-USA-Singapore Conf. on Biomech. 79 - 82 1995年04月

Mechanical Evaluation of Growth and Rupture of Aneurysm in Abdominal Aorta 査読有り

H. Yamada,E. Tanaka,S. Murakami

JSME Int. J. Series A 37 ( 2 ) 181 - 187 1994年04月

Changes in Hydraulic Resistance of a Coronary Artery in Relation to Stretching of the Surrounding Tissue 査読有り

P. Sipkema,H. Yamada,F.C.P. Yin

Proc. 13th Southern Biomed. Eng. Conf. 626 - 629 1994年04月

改良9Cr-1Mo鋼の繰返し応力クリープ,メカニカルラチェット挙動および振幅履歴依存性と統一型構造成式の精度評価査読有り

田中英一,山田宏

日本機械学会論文集 A編 59 ( 568 ) 2837 - 2843 1993年04月

腹部大動脈りゅうの成長と破裂に対する力学的評価査読有り

山田宏,田中英一,村上澄男

日本機械学会論文集 A編 58 ( 511 ) 1087 - 1092 1992年04月

血管壁に対する非弾性構成式の改良について査読有り

田中英一,山田宏,村上澄男

日本機械学会論文集A編 57 ( 534 ) 234 - 238 1991年04月

Inelastic Behavior of Modified 9Cr-1Mo Steel and Its Unified Constitutive Model 査読有り

E. Tanaka,S. Murakami,M. Mizuno,H. Yamada,K. Iwata

Proc. 6th Int. Conf. on Mechanical Behavior of Materials 781 - 786 1991年04月

An Improved Inelastic Constitutive Model of Blood Vessels Under Cyclic Pressurization 査読有り

E. Tanaka,H. Yamada

Proc. 6th Int. Conf. on Mechanical Behavior of Materials 3 739 - 744 1991年04月

Inelastic Constitutive Modeling for Blood Vessels Based on Viscoplasticity 査読有り

E. Tanaka,H. Yamada

Frontiers Med. Biol. Engng. ( 2 ) 3177 - 180 1990年04月

血管壁に対する弾-粘塑性構成式モデル査読有り

山田　宏

日本バイオレオロジー学会誌 4 ( 2 ) 88 - 96 1990年04月

内部変数理論に基づく粘塑性構成式による血管壁の応力解析査読有り

田中英一,山田宏

日本機械学会論文集A編 56 ( 529 ) 2011 - 2015 1990年04月

An Inelastic Constitutive Model of Blood Vessels 査読有り

E. Tanaka,H. Yamada

Acta Mechanica 82 ( 1-2 ) 21 - 30 1990年04月

血管壁に対する横等方非弾性構成式の定式化査読有り

田中英一,山田宏

日本機械学会論文集 A編 56 521 - 107-112 1990年04月

A Constitutive Model of Blood Vessels Under Cyclic Loading 査読有り

E. Tanaka,H. Yamada

Proc. of Plasticity '89 269 - 272 1989年07月

平滑筋活性状態での血管壁の変形挙動に対する構成式査読有り

村上澄男,山田宏,田中英一

日本機械学会論文集 A編 55 ( 513 ) 1022 - 1027 1989年04月

Isotropic and Anisotropic Inelastic Constitutive Models for Blood Vessels 査読有り

E. Tanaka,H. Yamada

Tissue Engineering -1989, Proc. ASME WAM 1989 123 - 126 1989年04月

血管壁に対する非弾性構成式の定式化査読有り

田中英一,山田宏

日本機械学会論文集 A編 54 ( 505 ) 1670 - 1676 1988年04月

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