KUMEMURA Momoko

写真a

Title

Associate Professor

Laboratory

2-4 Hibikino, Wakamatsu-ku, Kitakyushu-shi, Fukuoka

Degree 【 display / non-display

  • Tokyo Metropolitan University -  Doctor of Science  2005.03

Biography in Kyutech 【 display / non-display

  • 2018.04
    -
    Now

    Kyushu Institute of TechnologyGraduate School of Life Science and Systems Engineering   Department of Biological Functions Engineering   Associate Professor  

 

Publications (Article) 【 display / non-display

  • Nanopin – A MEMS based sensor for the analysis of single cell mechanical properties

    Momoko Kumemura, Lili C. Kudo, Zhongcai Ma, and Stanislav L. Karsten

    33rd IEEE International Conference on Micro Electro Mechanical Systems      311 - 314   2020.01  [Refereed]

    Canada  Vancouver  2020.01  -  2020.01

  • Real-time measurement of the physical properties of DNA-ligand complexes

    Deniz Pekin, Grégoire Perret, Momoko Kumemura, Laurent Jalabert, Samuel Meignan, Hiroyuki Fujita, Dominique Collard, and Mehmet C. Tarhan

    The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2019)      892 - 893   2019.10  [Refereed]

    Switzerland  Basel  2019.10  -  2019.10

  • Boyden chamber-based compartmentalized tumor spheroid culture system to implement localized anticancer drug treatment

    Shohei Kaneda , Jiro Kawada, Marie Shinohara, Momoko Kumemura, Ryohei Ueno, Tomoaki, Kawamoto, Kenji Suzuki, Beomjoon Kim , Yoshiho Ikeuchi , Yasuyuki Sakai, Dominique Collard, Hiroyuki Fujita, and Teruo Fujii

    Biomicrofluidics  ( AIP Publishing )  13   054111   2019.10  [Refereed]

    DOI

  • Optimization of Surface Treatment of MEMS Probes for Single-cell Capture and Release

    41. K. Hayashi,M. Kumemura, S. Kaneda, V. Menon, L. Jalabert, S. Tachikawa, M. C. Tarhan,T. Fujii, B.- J. Kim, H. Fujita

    Sensors and Materials  ( Myu Scientific Publishing )  31 ( 9 ) 2873 - 2881   2019.09  [Refereed]

  • Elucidating the mechanism of the considerable mechanical stiffening of DNA induced by the couple Zn<sup>2+</sup>/Calix[4]arene-1,3-O-diphosphorous acid

    Tauran Y., Tarhan M., Mollet L., Gerves J., Kumemura M., Jalabert L., Lafitte N., Byun I., Kim B., Fujita H., Collard D., Perret F., Desbrosses M., Leonard D., Goutaudier C., Coleman A.

    Scientific Reports    8 ( 1 )   2018.12  [Refereed]

     View Summary

    © 2018 The Author(s). The couple Calix[4]arene-1,3-O-diphosphorous acid (C4diP) and zinc ions (Zn2+) acts as a synergistic DNA binder. Silicon NanoTweezer (SNT) measurements show an increase in the mechanical stiffness of DNA bundles by a factor of >150, at Zn2+ to C4diP ratios above 8, as compared to Zinc alone whereas C4diP alone decreases the stiffness of DNA. Electroanalytical measurements using 3D printed devices demonstrate a progression of events in the assembly of C4diP on DNA promoted by zinc ions. A mechanism at the molecular level can be deduced in which C4diP initially coordinates to DNA by phosphate-phosphate hydrogen bonds or in the presence of Zn2+ by Zn2+ bridging coordination of the phosphate groups. Then, at high ratios of Zn2+ to C4diP, interdigitated dimerization of C4diP is followed by cross coordination of DNA strands through Zn2+/C4diP inter-strand interaction. The sum of these interactions leads to strong stiffening of the DNA bundles and increased inter-strand binding.

    DOI Scopus

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Publications (Books) 【 display / non-display

Conference Prsentations (Oral, Poster) 【 display / non-display

  • MEMSを用いた単一細胞の機械特性計測

    井上敦貴, 久米村百子

    化学とマイクロ・ナノシステム学会第40回研究会  (静岡県浜松市アクトシティ浜松)  2019.11  -  2019.11  化学とマイクロ・ナノシステム学会