Updated on 2022/09/22

 
KATO Tamaki
 
Scopus Paper Info  
Total Paper Count: 0  Total Citation Count: 0  h-index: 7

Citation count denotes the number of citations in papers published for a particular year.

Affiliation
Graduate School of Life Science and Systems Engineering Department of Biological Functions Engineering
Job
Associate Professor
External link

Research Interests

  • ペプチド

  • コンフォメーション

  • 生物有機科学

Research Areas

  • Nanotechnology/Materials / Chemistry and chemical methodology of biomolecules

Undergraduate Education

  • 1986.03   Kyushu University   Faculty of Science   Chemistry   Graduated   Japan

Post Graduate Education

  • 1991.03   Kyushu University   Graduate School, Division of Natural Science   Chemistry   Doctoral Program   Unfinished Course   Japan

Degree

  • Kyushu University  -  Doctor of Science   1994.09

Biography in Kyutech

  • 2014.04
     

    Kyushu Institute of Technology   Graduate School of Life Science and Systems Engineering   Department of Biological Functions Engineering   Associate Professor  

Biography before Kyutech

  • 1996.04 - 1998.03   カナダ国立研究機構バイオテクノロジー研究所   博士研究員   Canada

  • 1991.04 - 1995.03   東京農工大学工学部物質生物工学科   助手   Japan

Papers

  • Accessing the anti-microbial activity of cyclic peptide immobilized on reduced graphene oxide Reviewed

    Zheng A.L.T., Farrag H.N., Sabidi S., Kato T., Maeda T., Andou Y.

    Materials Letters   304   2021.12

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    Herein, we prepared and characterized two antimicrobial cyclic peptides immobilized on reduced graphene oxide (rGO) and accessed their anti-bacterial towards Gram-negative (Pseudomonas aeruginosa) and Gram-positive (Staphylococcus aureus) bacterias. The covalent interaction between the tyrosine and histidine based cyclic peptides and the rGO occurred via the carboxylic groups of the reduced graphene and the amino side chain groups of the cyclic peptides. A selective antibacterial effect is observed for the cyclic peptides functionalized rGO. The inhibition zone test showed that both the tyrosine and histidine cyclic based peptide immobilized on rGO exhibited higher anti-bacterial potency towards the bacteria in comparison to bare rGO which can be attributed to the synergistic effect of the antimicrobial peptide and rGO.

    DOI: 10.1016/j.matlet.2021.130621

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  • Design and synthesis of novel peptides to protect ferulic acid against ultraviolet radiation based on domain site iia of bovine serum albumin Reviewed

    Wu Y., Farrag H.N., Kato T., Li H., Ikeno S.

    Biomolecules   11 ( 9 )   2021.09

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    Ferulic acid (FA) is known for its excellent antioxidant properties, which can provide many health benefits. One of its drawbacks is its instability under UVA light, which limits its potency. In this study, the new peptides LW2 (QNKRFYFRKNQ) and CW2 (a cyclic form of LW2) were designed based on bovine serum albumin site IIA conformation. A UVA irradiation experiment was performed to investigate the protective ability of these peptides towards FA against UVA damage. The percentages of FA remaining under UV irradiation due to the protection of CW2 and LW2 were 83% and 76%, respectively. The results showed the importance of the cationic residues and hydrophobic residues included in the peptide sequences. Moreover, the cyclic rigid structure showed greater protective ability as compared to its linear counterpart.

    DOI: 10.3390/biom11091285

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  • Design, synthesis and antibacterial studies of novel cationic amphipathic cyclic undecapeptides and their linear counterparts against virulent bacterial strains Reviewed

    Farrag H.N., Maeda T., Kato T.

    Scientia Pharmaceutica   89 ( 1 )   1 - 11   2021.03

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    Bacteria have acquired resistance against almost all antibiotics because of the misuse of antibacterial agents and long periods of treatment. Antimicrobial peptides (AMPs) are one of the most encouraging candidates to solve this problem, as they possess high prokaryotic selectivity, and affect the bacteria by a unique mode of action. Novel cyclic undecapeptides (QNRNFYFNRNQ and QNRNFHFNRNQ) and their linear counterparts were investigated for their antibacterial activity against virulent strains. The minimal inhibitory concentration (MIC) values showed that tyrosine and histidine AMPs have promising antibacterial activity against virulent bacteria. The MIC values against the P. aeruginosa PA14, E. coli O157:H7 CR3, S. aureus 209P, and B. subtilis ATCC 6633 bacterial strains were evaluated for the cyclic peptide containing tyrosine, and their values were 6.25, 12.5, 12.5, and 12.5 µM, respectively. Meanwhile, for the linear form, they were 9.3, 12.5, 12.5, and 12.5 µM, respectively. The cyclic-peptide–containing histidines’ MIC values were 6.25, 3.1, 6.25, and 3.1 µM, respectively. Meanwhile, for the linear form, they were 3.1, 3.1, 3.1, and 6.25 µM, respectively. The antibacterial activities of the new AMPs were compared with that of gentamicin sulfate, and showed relatively higher potencies. Time-inhibition studies demonstrated the rapid antibacterial effects of the novel AMPs, which were more likely to be concentration-dependent, rather than time-dependent. At double the MIC concentration, all of the tested peptides exhibited relatively stable antibacterial effects up to 24 h, especially the peptides containing tyrosine, which showed an improved antibacterial effect.

    DOI: 10.3390/scipharm89010010

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  • The effect of a peptide substrate containing an unnatural branched amino acid on chymotrypsin activity Reviewed

    Yamawaki Y., Yufu T., Kato T.

    Processes   9 ( 2 )   1 - 8   2021.02

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    7-Amino-4-methylcoumarin (AMC) is a low molecular weight fluorescent probe that can be attached to a peptide to enable the detection of specific proteases, such as chymotrypsin, expressed in certain diseases. Because this detection depends on the specificity of the protease toward the peptidyl AMC, the development of specific substrates is required. To investigate the specificity of chymotrypsin, peptidyl AMC compounds incorporating four different amino acid residues were prepared by liquid-phase synthesis. Two unnatural amino acids, 2-amino-4-ethylhexanoic acid (AEH) and cyclohexylalanine (Cha), were used to investigate the substrate specificity as these amino acids have structures different from natural amino acids. AEH was synthesized using diethyl acetamidemalonate as a starting material. The substrate containing Cha had high hydrophobicity and showed a high reaction velocity with chymotrypsin. Although the AEH substrate with a branched side chain had high hydrophobicity, it showed a low reaction velocity. The substrate containing the aromatic amino acid phenylalanine was less hydrophobic than the Cha and AEH substrates, but chymotrypsin showed the highest specificity for this compound. These results demonstrated that the substrate specificity of chymotrypsin is not only affected by the hydrophobicity and aromaticity, but also by the structural expanse of amino acid residues in the substrate.

    DOI: 10.3390/pr9020242

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  • Design and synthesis of a new amphipathic cyclic decapeptide with rapid, stable, and continuous antibacterial effects Reviewed

    Farrag H.N., Metwally K., Ikeno S., Kato T.

    Pertanika Journal of Science and Technology   28 ( Special issue 2 )   183 - 196   2020.12

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    Pathogens can acquire high resistance against even the most powerful antibiotics because of the long periods of treatment and high usage of antimicrobial agents. In addition, the severe side effects of commonly used antibiotics can initiate secondary diseases or may lead to death. Antimicrobial peptides (AMPs) have been reported to exhibit prokaryotic selectivity and low microbial resistance. Furthermore, AMPs show a good ability to penetrate the cell walls of microorganisms. In this study, a cyclic decapeptide and its linear counterpart were synthesized by a standard solid phase peptide synthesis method (SPPS) in a quantitative yield of the linear decapeptide (97%) and a good yield of the cyclic form (45%). Antibacterial studies were performed using Escherichia coli (a widespread Gram-negative pathogen) and Bacillus thuringiensis as a representative Gram-positive pathogen. The minimal inhibitory concentration (MIC) values were evaluated by the broth microdilution method. The cyclic peptide and its linear counterpart exhibited MIC values of 0.16 and 0.3 mg/mL, respectively, against Escherichia coli. Against Bacillus thuringiensis, the peptides had the same MIC value of 0.24 mg/mL. Time-kill studies were performed using E. coli, which indicated a fast killing effect of both peptides (≥ 99% of the bacterial cells) after 1 h of incubation using a concentration of two times the MIC value for each peptide. Moreover, bacterial cell viability studies against E. coli carried out using a high bacterial concentration showed that both peptides have a maximum killing effect of more than 80% of the tested bacterial cells.

    DOI: 10.47836/pjst.28.S2.15

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  • Dual emissive bispyrene peptide probes for highly sensitive measurements of trypsin activity and evaluation of trypsin inhibitors Reviewed

    26 ( 12 )   3468 - 3473   2018.07

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    DOI: 10.1016/j.bmc.2018.05.021

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  • Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes Reviewed

    924 ( 1 )   2017.12

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    DOI: 10.1088/1742-6596/924/1/012006

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  • Efficient near infrared fluorescence detection of elastase enzyme using peptide-bound unsymmetrical squaraine dye Reviewed

    27   4024 - 4029   2017.06

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    DOI: 10.1016/j.bmcl.2017.07.057

  • Photophysical characterization and BSA interaction of the direct ring carboxy functionalized unsymmetrical NIR cyanine dyes Reviewed

    140   6 - 13   2017.01

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    DOI: 10.1016/j.dyepig.2017.01.015

  • Novel fluorescent substrates for detection of trypsin activity and inhibitor screening by self-quenching Reviewed

    26 ( 23 )   5736 - 5740   2016.12

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    DOI: 10.1016/j.bmcl.2016.10.053

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  • Photophysical investigations of squaraine and cyanine dyes and their interaction with bovine serum albumin Reviewed

    704 ( 1 )   2016.04

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    DOI: 10.1088/1742-6596/704/1/012012

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  • An efficient synthesis of SK-658 and its analogs as potent histone deacetylase inhibitors Reviewed

    Bioorganic Chemistry   59   145 - 150   2015.12

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    DOI: 10.1016/j.bioorg.2015.02.009

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  • Synthetic strategy for bicyclic tetrapeptides HDAC inhibitors using ring closing metathesis Reviewed

    127 ( 9 )   1563 - 1569   2015.09

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    DOI: 10.1007/s12039-015-0922-y

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  • Bicyclic tetrapeptide histone deacetylase inhibitors with methoxymethyl ketone and boronic acid zinc-binding groups Reviewed

    Bioorganic Chemistry   57   121 - 126   2014.12

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    DOI: 10.1016/j.bioorg.2014.10.003

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  • Bicyclic tetrapeptides as potent HDAC inhibitors: Effect of aliphatic loop position and hydrophobicity on inhibitory activity Reviewed

    Bioorganic & Medicinal Chemistry   22   3862 - 3870   2014.08

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    DOI: 10.1016/j.bmc.2014.06.031

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  • Design and synthesis of mono and bicyclic tetrapeptides thioester as potent inhibitor of histone Reviewed

    Amino Acids   46   2435 - 2444   2014.06

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    DOI: 10.1007/s00726-014-1800-5

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  • A convenient preparation of N ε-methyl-l-lysine derivatives and its application to the synthesis of histone tail peptides Reviewed

    Amino Acids   46 ( 5 )   1305 - 1311   2014.02

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    DOI: 10.1007/s00726-014-1690-6

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  • Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors Reviewed

    Bioorganic & Medicinal Chemistry   22   1268 - 1275   2014.02

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    DOI: 10.1016/j.bmc.2014.01.011

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  • Evaluation of functional groups on amino acids in cyclic tetrapeptides in histone deacetylase inhibition Reviewed

    Amino Acids   42   2103 - 2110   2012.06

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    DOI: 10.1007/s00726-011-0947-6

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  • Bicyclic peptides as potent inhibitors of histone deacetylases: Optimization of alkyl loop length Reviewed

    Nurul M. Islam,T. Kato,N. Nishino,H.-J. Kim,A. Ito,M. Yoshida

    Bioorganic & Medicinal Chemistry Letters   20   997999 - 997999   2010.02

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    DOI: 10.1016/j.bmcl.2009.12.054

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  • Interaction of aliphatic cap group in inhibition of histone deacetylases by cyclic tetrapeptides Reviewed

    N. Nishino,G. M. Shivashimpi,P. B. Soni,M. P. I. Bhuiyan,T. Kato,S.Maeda,T. G. Nishino,M. Yoshida

    Bioorganic & Medicinal Chemistry   16 ( 1 )   437 - 445   2008.01

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  • Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework Reviewed

    G. M. Shivashimpi,S. Amagai,T. Kato,N. Nishino,S. Maeda,T. G. Nishino,M. Yoshida

    Bioorganic & Medicinal Chemistry   15 ( 24 )   7830 - 7839   2007.12

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  • Smart Immobilization of oligopeptides through electrochemical deposition onto surface Reviewed

    H. Sakamoto,S. Ikeno,T. Kato,N. Nishino,T. Haruyama

    Analytica Chimica Acta   604 ( 1 )   76 - 80   2007.11

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  • Synthesis and characterization of dendritic poly(l-lysine) containing porphyrin-fullerene moieties Reviewed

    K. Kobata,J. Ogawa,S. S. Pandey,H. Oshima,T. Arai,T. Kato,N. Nishino

    Synthetic Metals   157   311 - 317   2007.04

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  • Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases Reviewed

    M. P. I. Bhuiyan,T. Kato,T. Okauchi,N. Nishino,S. Maeda,T. G. Nishino,M. Yoshida

    Bioorganic & Medicinal Chemistry   14 ( 10 )   3438 - 3446   2006.05

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  • Synthesis of Cyclic Imino Acids from α-Amino-ω-Bromoalkanoic Acids Reviewed

    Louis A. Watanabe,Mohammed P. I. Bhuiyan,Tamaki Kato,Norikazu Nishino

    Understanding Biology Using PeptidesProceedings of the American Peptide Society, 2005   499 - 500   2005.06

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    America   San Diego   2005.06.18  -  2005.06.23

  • Design and Synthesis of Histone Deacetylase Inhibitors by Side Chain Modification of 2-Amino-(n-1)-alkenoic Acids Reviewed

    Mohammed P. I. Bhuiyan,Tamaki Kato,Norikazu Nishino

    Understanding Biology Using PeptidesProceedings of the American Peptide Society, 2005   391 - 392   2005.06

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    America   San Diego   2005.06.18  -  2005.06.23

  • Design of a Library of Histone Deacetylase Inhibitors Based on Chlamydocin Reviewed

    N. Nishino,M. P. I. Bhuiyan,Y.Hirashima,L. A. Watanabe,P. Soni,T. Kato,T. Nishino,M. Yoshida

    Understanding Biology Using PeptidesProceedings of the American Peptide Society, 2005   393 - 394   2005.06

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    America   San Diego   2005.06.18  -  2005.06.23

  • Slipping of a histidine improved the peroxydase activity of de novo designed polypeptide packing an iron porphyrin Reviewed

    T. Arai,K. Ishibashi,K. Tomizaki,T. Kato,N. Nishino

    Tetrahedron   61 ( 16 )   4023 - 4030   2005.04

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  • Effect of hydrophobic amino acids on the conformational change of decapeptides in micellar environments Reviewed

    J. Kuwahara,H. Akisada,T. Kato,N. Nishino

    Colloid and Polymer Science   283 ( 7 )   747 - 752   2005.04

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  • Amyloid fibril formation of a simple decapeptide in a micellar environment Reviewed

    J. Kuwahara,H. Akisada,N. Wakayama,T. Kato,N. Nishino

    J. Oleo Science   54 ( 4 )   225 - 231   2005.03

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  • An efficient access to both enantiomers of pipecolic acid Reviewed

    L. A. Watanabe,S. Haranaka,B. Jose,M. Yoshida,T. Kato,M. Moriguchi,K. Soda,and N. Nishino

    Tetrahedron: Asymmetry   16 ( 4 )   903 - 908   2005.02

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  • Chlamydocin-hydroxamic acid analogues as histone deacetylase inhibitors Reviewed

    N. Nishino,B. Jose,R. Shinta,T. Kato,Y. Komatsu,M. Yoshida

    Bioorg. Med. Chem.   12   5777 - 5784   2004.12

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  • Effects of hydrophobic and electrostatic interactions on change in decapeptide conformation in micelle and liposome solution Reviewed

    J. Kuwahara,H. Akisada,T. Kato,N. Nishino

    J. Oleo Science   53 ( 12 )   619 - 626   2004.11

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  • Synthesis of novel fullerene amino acids and their multifullerene peptides Reviewed

    L. A. Watanabe,M. P. I. Bhuiyan,B. Jose,T. Kato,N. Nishino

    Tetrahedron Lett.   45 ( 38 )   7137 - 7140   2004.11

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  • Novel histone deacetylase inhibitors: cyclic tetrapeptide with trifluoromethyl and pentafluoroethyl ketones Reviewed

    B. Jose,Y. Oniki,T. Kato,N. Nishino,Y. Sumida,M. Yoshida

    Bioorg. Med. Chem. Lett.   14 ( 21 )   5343 - 5346   2004.11

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  • Spectroscopic characterization of an assembled pair of free-base and zinc porphyrins linked by the cyclic beta-sheet peptide Gramicidin S Reviewed

    T. Arai,K. Araki,N. Maruo,Y. Sumida,C. Korosue,K. Fukuma,T. Kato,N. Nishino

    New J. Chem.   28 ( 9 )   1151 - 1159   2004.09

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  • デノボデザインによるペルオキシダーゼ類似機能分子の創製Peroxidase-like functional molecule by de novo design

    T. Kato,N. Nishino

    日本農芸化学会誌   78 ( 8 )   38 - 40   2004.08

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  • Synthesis and properties of novel amino acids binding fullerene with alkylene spacer Reviewed

    M. P. I. Bhuiyan,L. A. Watanabe,B. Jose,T. Kato,N. Nishino

    Peptides Biology and ChemistryProceedings of the 2004 Chinese Peptide Symposium   250 - 252   2004.07

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    China   昆明   2004.07.03  -  2004.07.06

  • Syntheses and properties of stylostatin 1 and analogues Reviewed

    X.-H. Li,T. Kato,N. Nishino

    Peptides Biology and ChemistryProceedings of the 2004 Chinese Peptide Symposium   205 - 207   2004.07

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    China   昆明   2004.07.03  -  2004.07.06

  • Synthesis and histone deacetylase inhibitory activity of cyclic tetrapeptides containing a retrohydroxamate as zinc ligand Reviewed

    N. Nishino,D. Yoshikawa,L. A. Watanabe,T. Kato,B. Jose,Y. Komatsu,Y. Sumida,M. Yoshida

    Bioorg. Med. Chem. Lett.   14 ( 10 )   2427 - 2431   2004.05

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  • Toward an HDAC6 inhibitor: synthesis and conformational analysis of cyclic hexapeptide hydroxamic acid designed from alpha-tubulin sequence Reviewed

    B. Jose,S. Okamura,T. Kato,N. Nishino,Y. Sumida,and M. Yoshida

    Bioorg. Med. Chem.   12 ( 6 )   1351 - 1356   2004.03

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  • 酵素基質をアレイ化したバイオチップの基礎と展望The base and future of biochip with enzyme substrate array

    T. Kato,N. Nishino

    FED Review   3 ( 8 )   1 - 12   2004.03

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  • Cyclic tetrapeptides bearing a sulfhydryl group potently inhibit histone deacetylases Reviewed

    N. Nishino,B. Jose,S. Okamura,S. Ebisusaki,T. Kato,Y. Sumida,M. Yoshida

    Org. Lett.   5 ( 26 )   5079 - 5082   2003.12

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  • Synthesis of L-alpha-amino-omega-bromoalkanoic acid for side chain modification Reviewed

    L. A. Watanabe,B. Jose,T. Kato,N. Nishino,and M. Yoshida

    Tetrahedron Lett.   45 ( 3 )   491 - 494   2003.01

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  • Aniline-Hydroxylation Activity of a Flavin-linked baba-Type Polypeptide Packing an Iron Porphyrin Reviewed

    K. Tomizaki,H. Nishino,T. Arai,T. Kato,N. Nishino

    Chem. Lett.   32 ( 1 )   6 - 7   2003.01

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  • Complexation of 4,4'-Dipyridyl Derivatives Changed the Orientations of Metalloporphyrins Linked to the Cyclic Peptide Gramicidin S Reviewed

    T. Arai,K. Araki,K. Fukuma,T. Nakashima,T. Kato,N. Nishino

    Chem. Lett.   31 ( 11 )   1110 - 1111   2002.11

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  • CD Investigation of Porphyrin-Porphyrin Interaction with Links to Acyclic Sheet Peptide Self-Assembled in an Aqueous Media Reviewed

    T. Arai,M. Inudo,T. Ishimatsu,T. Sasaki,T. Kato,N. Nishino

    Chem. Lett.   30 ( 12 )   1240 - 1241   2001.12

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  • Substrate specificity of the streptococcal cysteine protease Reviewed

    M. Nomizu,G. Pietrzynski,T. Kato,P. Lachance,R. Menard,E. Ziomek

    The Journal of Biological Chemistry   276   44551 - 44556   2001.11

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  • Cyclic Hydroxamic-acid-containing Peptide 31, a Potent Synthetic Histone Deacetylase Inhibitor with Antitumor Activity Reviewed

    Y. Komatsu,K. Tomizaki,M. Tsukamoto,T. Kato,N. Nishino,S. Sato,T. Yamori,T. Tsuruo,R. Furumai,M. Yoshida,S. Horinouchi,H. Hayashi

    Cancer Research   61   4459 - 4466   2001.01

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  • The NMR Spectroscopic Evaluation of Immobility of a Crowd of Porphyrin Rings Combined with Dendritic Poly(L-lysine)s Reviewed

    T. Kato,N. Maruo,H. Akisada,T. Arai,N. Nishino

    Chem. Lett.   29 ( 8 )   890 - 891   2000.08

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  • De Novo Design of Hemoprotein Model with Peroxidase Activity toward Lipophilic Peroxide Reviewed

    T. Kato,K. Tomizaki,H. Nishino,T. Kato,A. Miike,N. Nishino

    Chem. Lett.   29 ( 6 )   648 - 649   2000.06

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  • Fluorescence Energy Transfer in Dendritic Poly(L-lysine)s Combining Thirty-Two Free Base- and Zinc(II)-Porphyrins in Scramble Fashion Reviewed

    T. Kato,M. Uchiyama,N. Maruo,T. Arai,N. Nishino

    Chem. Lett.   29 ( 2 )   144 - 145   2000.02

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  • The conformation of de novo designed amphiphilic peptides with six or nine L-2-(2,2,2-trifluoroethyl) glycines as the hydrophobic amino acid Reviewed

    T. Arai,T. Imachi,T. Kato,N. Nishino

    Bull. Chem. Soc. Jpn.   73   439 - 445   2000.02

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  • Hemispherical Synthesis of Dendritic Poly(L-lysine) Combining Sixteen Free-Base Porphyrins and Sixteen Zinc Porphyrins Reviewed

    加藤 珠樹

    Chem. Commun   1999   2057 - 2058   1999.04

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Conference Prsentations (Oral, Poster)

  • Temperature Effect on the Control of Collagen Triple Helix Formation by Photo-isomerization of Azobenzene

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    Event date: 2022.03.23 - 2022.03.26   Language:Japanese  

  • INHIBITION AND MOLECULAR DOCKING STUDIES ON ANGIOTENSIN I-CONVERTING ENZYME BY PEPTIDES FROM AN ELASTASE-TREATED HYDROLYSATE OF PORCINE AORTIC ELASTIN

    T. Hatakenaka, M. Yoshimizu, T. Kato, K. Okamoto

    The 57th Japanese Peptide Symposium  The Japanese Peptide Society

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    Event date: 2020.11.09 - 2020.11.11   Language:English  

  • Novel Oligopeptides with angiotensin I-converting enzyme inhibitory activity found in an elastase-treated hydrolysate of porcine aortic elastin

    T. Hatakenaka, T. Kato, K. Okamoto

    35th European Peptide Symposium  European Peptide Society

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    Event date: 2018.08.26 - 2018.08.31   Language:English   Country:Ireland  

  • 蛍光性ペプチドとリシンデンドリマーを用いた酵素活性の検出

    服部司 生命体工学研究科生体機能専攻

    日本化学会第91春季年会(2011) 

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    Event date: 2011.03.26 - 2011.03.29   Language:Japanese  

  • 固定化した蛍光性ペプチドによる酵素活性の検出

    山本祥太郎 物質工学科応用化学コース

    日本化学会第91春季年会(2011) 

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    Event date: 2011.03.26 - 2011.03.29   Language:Japanese  

  • 環状ペプチドナノチューブ形成の解析

    武哲 生命体工学研究科生体機能専攻

    日本化学会第91春季年会(2011) 

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    Event date: 2011.03.26 - 2011.03.29   Language:Japanese  

  • Synthesis and characterization of antimicrobial peptide surfactant with dendritic lysine groups

    5th International Peptide Symposium 

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    Event date: 2010.12.04 - 2010.12.09   Language:English  

  • Cyclic Tetrapeptides containing iso-Propylglycine as Histone Deacetylase Inhibitors

    5th International Peptide Symposium 

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    Event date: 2010.12.04 - 2010.12.09   Language:English  

  • Self-assembling Cyclic Hexapeptides for Peptide Nanotube Formation

    5th International Peptide Symposium 

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    Event date: 2010.12.04 - 2010.12.09   Language:English  

    CiNii Article

  • Anti-allergic action of strawberry extract in vitro

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    Event date: 2010.09.01 - 2010.09.04   Language:English  

  • Thirteen-membered Cyclic Tetrapeptides as Histone Deacetylase Inhibitors

    11th International Chinese Peptide Symposium 

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    Event date: 2010.07.05 - 2010.07.08   Language:English  

  • Remodeling of Cyclic Tetrapeptides Framework of Chlamydocin as Histone Deacetylase Inhibitors

    11th International Chinese Peptide Symposium 

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    Event date: 2010.07.05 - 2010.07.08   Language:English  

  • Role of prolyl residue in cyclic tetrapeptides designed as histone deacetylase inhibitors

    11th International Chinese Peptide Symposium 

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    Event date: 2010.07.05 - 2010.07.08   Language:English  

  • D-アミノ酸を用いない環状ペプチドナノチューブの形成

    田中大地 生命体工学研究科生体機能専攻

    日本化学会第90春季年会 

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    Event date: 2010.03.26 - 2010.03.29   Language:Japanese  

  • 環状ペプチドの集積によるペプチドナノチューブの構築

    田中大地 生命体工学研究科生体機能専攻

    第46 回ペプチド討論会 

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    Event date: 2009.11.04 - 2009.11.06   Language:Japanese  

  • Nε-メチル-L-リシンの簡便合成とヒストンテールペプチドへの導入

    遅弘放 生命体工学研究科生体機能専攻

    第46 回ペプチド討論会 

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    Event date: 2009.11.04 - 2009.11.06   Language:Japanese  

  • 環状テトラペプチド型ヒストン脱アセチル化酵素阻害剤の立体構造に与える側鎖結合ループの影響

    イスラム M ヌルル 生命体工学研究科生体機能専攻

    第46 回ペプチド討論会 

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    Event date: 2009.11.04 - 2009.11.06   Language:Japanese  

  • Design and Synthesis of Chlamydocin Analogues as Histone Deacetylase Inhibitors by Introduction of Various Imino Acids

    8th Australian Peptide Conference 

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    Event date: 2009.10.11 - 2009.10.16   Language:English  

  • Design and Synthesis of Histone Deacetylase Inhibitors by Replacement of Aib in Chlamydocin Hydroxamic Acid Analogues

    8th Australian Peptide Conference 

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    Event date: 2009.10.11 - 2009.10.16   Language:English  

  • ポリペプチドを結合したポルフィリンを触媒とした水からの水素発生

    小畑菜緒 生命体工学研究科生体機能専攻

    2009光化学討論会 

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    Event date: 2009.09.16 - 2009.09.18   Language:Japanese  

  • ピペコリン酸のコラーゲンモデルペプチド中における挙動

    田中雄二 九州共立大学

    第45回ペプチド討論会 

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    Event date: 2008.10.29 - 2008.10.31   Language:Japanese  

  • 環状ペプチドの集積によるペプチドナノチューブの構築

    本人

    第45回ペプチド討論会 

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    Event date: 2008.10.29 - 2008.10.31   Language:Japanese  

  • Pipecolic Acid Disrupts Collagen Triple Helix Structure in Model Peptides

    30th European Peptide Symposium 

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    Event date: 2008.09.01 - 2008.09.05   Language:English  

  • Unusual Cleavage of Tripeptides Containing Pipecolic Acid

    30th European Peptide Symposium 

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    Event date: 2008.09.01 - 2008.09.05   Language:English  

  • Self-assembling Cyclic Peptides for Peptide Nanotube Formation

    30th European Peptide Symposium 

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    Event date: 2008.09.01 - 2008.09.05   Language:English  

  • Design and Synthesis of Cyclic Tetrapeptides bearing Methoxymethyl Ketone at Side Chain as Histone Deacetylase Inhibitors

    10th Chinese International Peptide Symposium (CPS-2008) 

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    Event date: 2008.07.01 - 2008.07.05   Language:English  

  • βαβα-型人工ペルオキシダーゼ:界面活性剤添加効果

    大石 直人 生命体工学研究科生体機能専攻

    第57回高分子学会年次大会 

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    Event date: 2008.05.28 - 2008.05.30   Language:Japanese  

  • 環状ペプチド上のポルフィリンとフラーレンC60 の相互作用

    山口修司 生命体工学研究科生体機能専攻

    第57回高分子学会年次大会 

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    Event date: 2008.05.28 - 2008.05.30   Language:Japanese  

  • ピペコリン酸を導入したコラーゲンモデルペプチドの合成と性質

    Son Ram Shankar 生命体工学研究科生体機能専攻

    第57回高分子学会年次大会 

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    Event date: 2008.05.28 - 2008.05.30   Language:Japanese  

  • グリシンを導入したHDAC 阻害剤の構造と活性

    石井寛教 生命体工学研究科生体機能専攻

    日本化学会第89春季年会 

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    Event date: 2008.03.27 - 2008.03.30   Language:Japanese  

  • ポルフィリン含有環状ヘキサペプチドの合成とフラーレンC60との相互作用

    前原裕紀 生命体工学研究科生体機能専攻

    日本化学会第89春季年会 

     More details

    Event date: 2008.03.27 - 2008.03.30   Language:Japanese  

  • NMR による環状ヘキサペプチドナノチューブ形成の解析

    寺西瞳 生命体工学研究科生体機能専攻

    日本化学会第89春季年会 

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    Event date: 2008.03.27 - 2008.03.30   Language:Japanese  

  • (D-Pro-D-Pro-Gly)nの合成と構造解析

    完山陽秀 生命体工学研究科生体機能専攻

    日本化学会第89春季年会 

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    Event date: 2008.03.27 - 2008.03.30   Language:Japanese  

  • α-アルキルアミノ酸を含む環状ジペプチドのジアステレオマー分離によるアミノ酸光学分割

    高橋悟 生命体工学研究科 生体機能専攻

    第44回ペプチド討論会 

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    Event date: 2007.11.07 - 2007.11.09   Language:English  

  • ヒストン脱アセチル化酵素阻害剤としてのヒドロキサム酸含有HC-toxinおよびクラミドシンアナローグ

    大塚康彦 生命体工学研究科 生体機能専攻

    第44回ペプチド討論会 

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    Event date: 2007.11.07 - 2007.11.09   Language:English  

  • 非環状イミノ酸を含むクラミドシンおよびHC-toxinのヒドロキサム酸アナローグの合成及びヒストン脱アセチル化酵素阻害における立体構造の影響

    白石いずみ 生命体工学研究科 生体機能専攻

    第44回ペプチド討論会 

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    Event date: 2007.11.07 - 2007.11.09   Language:English  

  • ポルフィリンおよびフラーレンC60を一組として担持する環状ペプチドの合成と性質

    山口修司 生命体工学研究科 生体機能専攻

    第44回ペプチド討論会 

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    Event date: 2007.11.07 - 2007.11.09   Language:English  

  • コラーゲンモデルペプチド中におけるピペコリン酸のらせん形成能

    ソヌ ラム シャンカール 生命体工学研究科 生体機能専攻

    第44回ペプチド討論会 

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    Event date: 2007.11.07 - 2007.11.09   Language:English  

  • Design of Histone Deacetylase Inhibitors with Chlamydocin Framework containing Various Imino Acids instead of Proline Residue

    4th International Peptide Symposium 

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    Event date: 2007.10.21 - 2007.10.25   Language:English  

  • Synthesis of HC-toxin Hydroxamic Acid Analogs and Their Inhibitory Activity toward Histone Deacetylases

    4th International Peptide Symposium 

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    Event date: 2007.10.21 - 2007.10.25   Language:English  

  • Self-assembling cyclic hexapeptides for peptide nanotube formation

    4th International Peptide Symposium 

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    Event date: 2007.10.21 - 2007.10.25   Language:English  

  • ヒスチジンクラスターにより基板導入可能な基質の設計合成

    高橋悟(生命体工学研究科生体機能専攻)

    第44回化学関連支部合同九州大会 

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    Event date: 2007.07.07   Language:Japanese  

  • ポルフィリンとフラーレンを一つずつ有する環状デカペプチドの合成

    山口修司(生命体工学研究科生体機能専攻)

    第44回化学関連支部合同九州大会 

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    Event date: 2007.07.07   Language:Japanese  

  • ポリペプチド構造体に結合したポルフィリン(Fe)錯体の酸化反応活性

    大石直人 生命体工学研究科生体機能専攻

    第56回高分子学会年次大会 

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    Event date: 2007.05.29 - 2007.05.31   Language:Japanese  

  • ペプチドナノチューブを形成する環状ヘキサペプチド集積体

    吉崎舞 生命体工学研究科生体機能専攻

    第56回高分子学会年次大会 

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    Event date: 2007.05.29 - 2007.05.31   Language:Japanese  

  • ピペコリン酸含有コラーゲンモデルペプチドの異常開裂

    イスラム モハメド ヌルル 生命体工学研究科生体機能専攻

    日本化学会第88春季年会 

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    Event date: 2007.03.26 - 2007.03.30   Language:Japanese  

  • ヒスチジンクラスターにより基板導入されたプロテアーゼ基質の評価

    林田寿子 生命体工学研究科生体機能専攻

    日本化学会第88春季年会 

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    Event date: 2007.03.26 - 2007.03.30   Language:Japanese  

  • β-ストランドおよびα-へリックス上の閉環メタセシス反応

    大石直人 生命体工学研究科生体機能専攻

    日本化学会第88春季年会 

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    Event date: 2007.03.26 - 2007.03.30   Language:Japanese  

  • 環状ヘキサペプチドの集積によるペプチドナノチューブの構築

    本人

    日本化学会第88春季年会 

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    Event date: 2007.03.26 - 2007.03.30   Language:Japanese  

  • デノボデザインによるペルオキシダーゼ様人工酵素モデルの構築

    大石直人 生命体工学研究科生体機能専攻

    日本化学会第87春季年会 

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    Event date: 2007.03.25 - 2007.03.28   Language:Japanese  

  • ヒスチジンクラスターにより基板導入可能な基質の設計合成

    軸丸真名 生命体工学研究科生体機能専攻

    日本化学会第87春季年会 

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    Event date: 2007.03.25 - 2007.03.28   Language:Japanese  

  • 環状ペプチドの集積によるペプチドナノチューブの構築

    吉崎舞 生命体工学研究科生体機能専攻

    日本化学会第87春季年会 

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    Event date: 2007.03.25 - 2007.03.28   Language:Japanese  

  • 新規HDAC 阻害剤の設計合成と複合体モデルの構築

    平島義紀 生命体工学研究科生体機能専攻

    日本化学会第87春季年会 

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    Event date: 2007.03.25 - 2007.03.28   Language:Japanese  

  • Toward Potent HDAC Inhibitor Design : Insights from Homology Modeling and Docking Simulation of HDAC and Its Inhibitors

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    Event date: 2006.11.12 - 2006.11.16   Language:English  

  • Aromatic Ring Shifting in Chlamydocin Framework for Specific Inhibition of Histone Deacetylase Paralogs

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    Event date: 2006.11.05 - 2006.11.08   Language:English  

  • Design and Synthesis of Histone Deacetylase Inhibitors Containing Hydroxy-Imino-Acids as the Capping Group

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    Event date: 2006.11.05 - 2006.11.08   Language:English  

  • 電解析出Ni結晶によるヒスチジンクラスターの基板への導入

    (奥村欣也 生命体工学研究科 生体機能専攻)

    第55回高分子討論会 

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    Event date: 2006.09.20 - 2006.09.22   Language:Japanese  

  • DESIGN AND SYNTHESIS OF HISTONE DEACETYLASE INHIBITORS CONTAINING THIOETHER MOIETY AS THE FUNCTIONAL GROUP

    29th European Peptide Symposium 

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    Event date: 2006.09.03 - 2006.09.08   Language:English  

  • DESIGN AND SYNTHESIS OF HISTONE DEACETYLASE INHIBITORS BY AROMATIC RING SHIFTING IN CHLAMYDOCIN FRAMEWORK

    29th European Peptide Symposium 

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    Event date: 2006.09.03 - 2006.09.08   Language:English  

  • EFFECTS OF HISTONE DEACETYLASE INHIBITORS BASED ON CHLAMYDOCIN ON TYPE 2 DIABETIC MODEL MICE

    29th European Peptide Symposium 

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    Event date: 2006.09.03 - 2006.09.08   Language:English  

  • ポルフィリン/フラーレン C60 システムを有するオリゴ(L-リシン)デンドロン

    新井 徹 物質工学科 応用化学コース

    第16回バイオ・高分子シンポジウム 

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    Event date: 2006.08.01 - 2006.08.02   Language:Japanese  

  • ポルフィリン-フラーレンC60 システムを有するオリゴ(L-リシン)デンドロンの合成とその性質

    大嶋 秀俊 生命体工学研究科 生体機能専攻

    第55回高分子学会年次大会 

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    Event date: 2006.05.24 - 2006.05.26   Language:Japanese  

  • ヒスチジンクラスターの形成と電気化学的基板修飾

    奥村 欣也 生命体工学研究科 生体機能専攻

    第55回高分子学会年次大会 

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    Event date: 2006.05.24 - 2006.05.26   Language:Japanese  

  • ペプチドのβ構造形成による線維状ナノ構造体の構築

    (西尾奈津子 生命体工学研究科 生体機能専攻)

    日本化学会第86春季年会 

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    Event date: 2006.03.28 - 2006.03.30   Language:Japanese  

  • ヒストン脱アセチル化酵素阻害剤のスペーサー修飾

    (天海 聡 生命体工学研究科 生体機能専攻)

    日本化学会第86春季年会 

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    Event date: 2006.03.27 - 2006.03.30   Language:Japanese  

  • メチル基修飾環状イミノ酸の合成とクラミドシンアナローグへの導入

    本人

    日本化学会第86春季年会 

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    Event date: 2006.03.27 - 2006.03.30   Language:Japanese  

  • 水酸基含有環状イミノ酸を導入したクラミドシンアナローグの合成

    平島義紀 生命体工学研究科 生体機能専攻)

    日本化学会第86春季年会 

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    Event date: 2006.03.27 - 2006.03.30   Language:Japanese  

  • ポルフィリン-フラーレンC60 システムを内包した高分子ナノ微粒子

    (小川淳也 生命体工学研究科 生体機能専攻)

    第15回インテリジェント材料・システムシンポジウム 

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    Event date: 2006.03.15   Language:Japanese  

  • Polymeric nanospheres containing porphyrin-fullerene C60 hybrid

    小川淳也 生命体工学研究科 生体機能専攻

    2005 Pusan-Kyepngnam/Kyushu-Seibu Joint Symposium on High Polymers(12th)and Fibers(10th) 

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    Event date: 2005.11.03 - 2005.11.05   Language:Japanese  

  • 環状テトラペプチドの側鎖にトリフルオロアセトニル基とチオエーテルを導入したHDAC阻害剤の設計合成

    (平島義紀 生命体工学研究科 生体機能専攻)

    第42回ペプチド討論会 

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    Event date: 2005.10.27 - 2005.10.29   Language:Japanese  

  • メチル基、ヒドロキシル基で修飾された環状イミノ酸の簡便合成

    (Mohammed P. I. Bhuiyan 生命体工学研究科 生体機能専攻)

    第42回ペプチド討論会 

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    Event date: 2005.10.27 - 2005.10.29   Language:Japanese  

  • ポルフィリン-フラーレンC60 システムを内包した高分子ナノ微粒子

    (小川淳也 生命体工学研究科 生体機能専攻)

    第54回高分子討論会 

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    Event date: 2005.09.22 - 2005.09.23   Language:Japanese  

  • Design of a Library of Histone Deacetylase Inhibitors Based on Chlamydocin

    平島義紀 生命体工学研究科 生体機能専攻

    19th American Peptide Symposium 

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    Event date: 2005.06.18 - 2005.06.23   Language:Japanese  

  • Design and Synthesis of Histone Deacetylase Inhibitors by Side Chain Modification of 2-Amino-(n-1)-alkenoic Acids

    19th American Peptide Symposium 

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    Event date: 2005.06.18 - 2005.06.23   Language:English  

  • Synthesis of Cyclic Imino Acids from α-Amino-ω-Bromoalkanoic Acids

    19th American Peptide Symposium 

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    Event date: 2005.06.18 - 2005.06.23   Language:English  

  • ポルフィリン-フラーレンハイブリッドを有するオリゴ(L-リシン)デンドロンの合成

    小川 淳也 生命体工学研究科 生体機能専攻

    第54回高分子学会年次大会 

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    Event date: 2005.05.25 - 2005.05.27   Language:Japanese  

  • 5―ヒドロキシ―L―ピペコリン酸の簡便合成

    西野憲和 生命体工学研究科 生体機能専攻

    日本化学会第85春季年会 

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    Event date: 2005.03.26 - 2005.03.29   Language:Japanese  

  • 側鎖にヒドロキサム酸を含有する環状テトラペプトイドの合成

    平島義紀 生命体工学研究科 生体機能専攻

    日本化学会第85春季年会 

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    Event date: 2005.03.26 - 2005.03.29   Language:Japanese  

  • 側鎖末端に二重結合を有するアミノ酸の簡便合成とその応用

    Bhuiyan, Mohammed P. I 生命体工学研究科 生体機能専攻

    日本化学会第85春季年会 

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    Event date: 2005.03.26 - 2005.03.29   Language:Japanese  

  • SYNTHESIS OF NOVEL FULLERENE AMINO ACIDS AND MULTIFULLERENE PEPTIDES

    3rd International and 28th European Peptide Symposium  

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    Event date: 2004.09.05 - 2004.09.10   Language:English  

  • A BRIDGE BETWEEN NATURAL PRODUCTS TO CANCER DRUGS: TOWARD SUBCLASS SELECTIVE CYCLIC-PEPTIDE-INHIBITORS OF HISTONE DEACETYLASES

    3rd International and 28th European Peptide Symposium  

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    Event date: 2004.09.05 - 2004.09.10   Language:English  

  • Syntheses and properties of stylostatin 1 and analogues

    X.-H. Li 大連理工大学環境生命学院

    Peptides Biology and ChemistryProceekings of the 2004 Chinese Peptide Symposium 

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    Event date: 2004.07.03 - 2004.07.06   Language:Japanese  

  • Synthesis and properties of novel amino acids binding fullerene with alkylene spacer

    西野 憲和 生命体工学研究科 生体機能専攻

    Peptides Biology and ChemistryProceekings of the 2004 Chinese Peptide Symposium 

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    Event date: 2004.07.03 - 2004.07.06   Language:Japanese  

  • 側鎖にフラーレンを有する新規アミノ酸誘導体の合成

    Bhuiyan, Mohammed P. I. 生命体工学研究科 生体機能専攻

    日本化学会第84春季年会 

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    Event date: 2004.03.26 - 2004.03.29   Language:Japanese  

  • 西洋わさびペルオキシダーゼによるジチロシン含有ペプチドの合成

    安東隆文 生命体工学研究科 生体機能専攻

    日本化学会第84春季年会 

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    Event date: 2004.03.26 - 2004.03.29   Language:Japanese  

  • ポルフィリン環とフラーレンC60 を2:1 で結合させたオリゴ(L-リシン)デンドロンの合成

    小川淳也 生命体工学研究科 生体機能専攻

    第14回インテリジェント材料・システムシンポジウム 

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    Event date: 2004.03.09 - 2004.03.10   Language:Japanese  

  • Endeavors toward a Specific Inhibitor for HDAC6

    18th American Peptide Symposium  

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    Event date: 2003.07.19 - 2003.07.23   Language:English  

  • Design and Synthesis of Porphyrin Centered Dendritic Poly(L-Kysine)

    18th American Peptide Symposium  

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    Event date: 2003.07.19 - 2003.07.23   Language:English  

  • Cyclic Tetrapeptides Containing a Zinc Ligand as Novel Histone Deacetylase Inhibitors

    18th American Peptide Symposium  

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    Event date: 2003.07.19 - 2003.07.23   Language:English  

  • 末端修飾のためのα ―アミノ―ω ―ブロモアルカン酸の合成

    渡邉路維 生命体工学研究科 生体機能専攻

    日本化学会第83春季年会 

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    Event date: 2003.03.26 - 2003.03.29   Language:Japanese  

  • L―およびD―ピペコリン酸の新規合成法

    西野憲和 生命体工学研究科 生体機能専攻

    日本化学会第83春季年会 

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    Event date: 2003.03.18 - 2003.03.21   Language:Japanese  

  • ジスルフィド結合を有する環状テトラペプチドの設計合成とヒストンデアセチラーゼ阻害

    岡村真二 生命体工学研究科 生体機能専攻

    日本化学会第81春季年会 

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    Event date: 2002.03.26 - 2002.03.29   Language:Japanese  

  • HDAC 活性測定を目的とした蛍光性基質の設計合成

    原中沙緒理 生命体工学研究科 生体機能専攻

    日本化学会第81春季年会 

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    Event date: 2002.03.26 - 2002.03.29   Language:Japanese  

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