研究者詳細 - 玉川　雅章

論文 - 玉川　雅章

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Mechanism of Damage for Two Living Tissue Cells by Plane Shock Waves in Water (Mathematical Model of Two Cells) 査読有り

M. Tamagawa,T.Akamats

Proc. of 21st International Symposium on Shock Waves 5610 - 5610 1997年07月

Prediction of Hemolysis in Turbulent Shear Blood Flows (Effects of Turbulence and Wall) 査読有り

M. Tamagawa,T.Sano,T.Akamatsu

Proc. of Int. Conf. on New Frontiers in Biomechanical Engineering 143 - 144 1997年07月

Effects of Shock waves on living tissues(Numerical Analysis of a Propagating Pressure wave toward Living Tissue) 査読有り

M. Tamagawa,T.Akamatsu

JSME International Journal Series B 39 ( 4 ) 1996年11月

Effects of shock waves on living tissues. (Numerical analysis of a propagating pressure wave toward living tissue) 査読有り国際誌

Tamagawa M., Akamatsu T.

JSME International Journal, Series B: Fluids and Thermal Engineering 39 ( 4 ) 714 - 720 1996年11月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

This paper describes pressure wave analysis in order to examine the effects of shock waves on living tissues. From the comparison of displacements of living tissue models by FEM with that obtained by experiments, dynamic properties of living tissue (rat's kidney) are determined. Using these properties of the living tissues in shock compression (solid-state equation), the flow fields in two layers that consist of air and the living tissue, and in three layers that consist of air, water, and the living tissue are numerically obtained. It is found that the incident time derivative of pressure in the living tissue is smaller than that of pressure in air and water. Hence, the effect of the living tissue depends on the relaxation of pressure waves and duration of exposure.

DOI： 10.1299/jsmeb.39.714

Scopus

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Prediction of Hemolysis in Turbulent Shear Orifice Flow 査読有り

(M. Tamagawa,T.Akamatsu

Artificial Organs 20 ( 6 ) 553 - 559 1996年10月

Damage to Living Tissue Cells by Plane Shock Waves in Water and its Mechanism 査読有り

M. Tamagawa,T.Akamatsu

Proc of 19th Int. Congress of Theoretical and Applied Mechanics 707 - 707 1996年07月

オリフィス管内せん断血流の溶血特性予測査読有り

玉川雅章，斉藤圭司朗，赤松映明

日本機械学会論文集 B編 62 ( 597 ) 1747 - 1753 1996年05月

Prediction of hemolysis tendency by shear stress in a pipe orifice blood flow 査読有り国際誌

Tamagawa M., Saitoh K., Akamatsu T.

Nippon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B 62 ( 597 ) 1747 - 1753 1996年05月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

This paper describes a method of predicting hemolysis induced by turbulent shear stress (Reynolds stress) in simplified orifice pipe flow. In a centrifugal blood pump, serious hemolysis occurs at the impeller or the casing edge. The turbulent shear stress computed using a low-Reynolds number k-ε model near the edge proves to be several hundred times the laminar shear stress (molecular shear stress). The peak turbulent shear stress is about 2 500 Pa, which is much larger than that obtained from a conventional hemolysis test using viscometer. Then the threshold of turbulent shear stress for hemolysis is determined by comparing with that obtained in hemolysis experiments of pipe-orifice blood flow.

DOI： 10.1299/kikaib.62.1747

Scopus

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衝撃波の生体組織細胞（赤血球）に及ぼす影響（赤血球損傷と球殻内部流体モデルによる数値解析）査読有り

玉川雅章，吉田恵一郎，赤松映明

日本機械学会論文集　Ｂ編 62 ( 594 ) 613 - 619 1996年02月

Effects of shock waves in living tissue cell (red blood cell) (Damage of red blood cell and mathematical analysis of deformation model using spherical shell filled with liquid) 査読有り

Tamagawa M., Yoshida K., Akamatsu T.

Nippon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B 62 ( 594 ) 613 - 619 1996年02月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

This paper describes damage to living tissue cells induced by plane shock waves. It is an effective method for sensing injury to living tissue cells using pseudo-living cells. In this study, micro-capsules are used to estimate the degree of damage when subjected to shock waves. Mathematical models that can analyze displacement of living tissue cells and pressure in fluid when subjected to shock waves are evaluated. An elastic spherical shell is modeled to fit the biological data. Using stationary and transient analysis of spherical shell, the dynamic characteristics of the living cells (red blood cells and the micro-capsules) are obtained. The results show that damage to living tissue cells depends on (1) the elastic modulus of the cell, (2) the bulk modulus of intracellular material and (3) the thickness of cell membrane.

DOI： 10.1299/kikaib.62.613

Scopus

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030085712&origin=inward

Prediction of hemolysis in turbulent shear orifice flow 査読有り国際誌

Tamagawa M., Akamatsu T., Saitoh K.

Artificial Organs 20 ( 5 ) 553 - 559 1996年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

This study proposes a method of predicting hemolysis induced by turbulent shear stress (Reynolds stress) in a simplified orifice pipe flow. In developing centrifugal blood pumps, there has been a serious problem with hemolysis at the impeller or casing edge; because of flow separation and turbulence in these regions. In the present study, hemolysis caused by turbulent shear stress must occur at high shear stress levels in regions near the edge of an orifice pipe flow. We have computed turbulent shear flow using the low-Reynolds number κ - ε model. We found that the computed turbulent shear stress near the edge was several hundreds times that of the laminar shear stress (molecular shear stress). The peak turbulent shear stress is much greater than that obtained in conventional hemolysis testing using a viscometer apparatus. Thus, these high turbulent shear stresses should not be ignored in estimating hemolysis in this blood flow. Using an integrated power by shear force, it is optimimal to determine the threshold of the turbulent shear stress by comparing computed stress levels with those of hemolysis experiments of pipe orifice blood flow.

DOI： 10.1111/j.1525-1594.1996.tb04479.x

Scopus

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0030017653&origin=inward

Experimental and Mathematical Injury Model of Living Tissue Cell Induced by Plane Shock Waves 査読有り

M. Tamagawa,T.Akamatsu

Proc. 20th Int. Shock Wave Symp. 1649 - 1654 1995年07月

衝撃波の生体組織に及ぼす影響（第２報衝撃波が生体組織に入射したときの圧力波（縦波）の数値解析）査読有り

玉川雅章，赤松映明

日本機械学会論文集　Ｂ編 60 ( 579 ) 3768 - 3774 1994年09月

衝撃波の生体組織に及ぼす影響（第１報非破膜式衝撃波管を用いた生体組織変性試験用単発鋸歯状圧力波発生装置の開発と動物実験）査読有り

玉川雅章，赤松映明，渡辺決，内田睦，今出陽一朗

日本機械学会論文集　Ｂ編 60 ( 579 ) 3762 - 3767 1994年09月

Effects of the Shock Waves on Living Tissue 査読有り

M. Tamagawa,T.Akamatsu

Advances in Bioengineering, BED-vol.28, ASME 95 - 96 1993年12月

Effects of Shock Waves on Living Tissues Using Shock Tube for Bio-test 査読有り

M. Tamagawa,T.Akamatsu

Proc.19th Int.Shock Wave Symp ，Springer Verlag 3 219 - 221 1993年07月

Effects of the Shock Wave on Living Tissue 査読有り

M. Tamagawa,T.Akamatsu

Proc.7th Int. Conf. on Biomedical Engineering 219 - 221 1992年12月

Development of Test Apparatus for the Shock Induced Injury of Living Tissue 査読有り

M. Tamagawa,T.Akamatsu

Proc. 18th Int. Shock Wave Symp 1177 - 1180 1991年07月

Error Estimate and Flow Analysis Using Spectral Element Method 査読有り

T.Kobayashi,M.Tamagawa

Proc. the 2nd Japan-Soviet Union Joint Symp. on CFD 45 - 52 1990年07月

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