研究者詳細 - 玉川　雅章

論文 - 玉川　雅章

分割表示219 件中 101 - 120 件目／全件表示 >>

Observation of bubble deformation process in a microcapsule for developing drug delivery systems using shock waves and ultrasonic waves 査読有り国際誌

Tamagawa M.

ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 2 881 - 883 2011年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes development of microcapsule using underwater shock waves, especially (1) the trial of making polymer microcapsules including a bubble and disintegration tests by shock waves, (2) analysis of a bubble deformation process in a polymer capsule by pressure wave, (3) the trails of making liposome microcapsules and disintegration tests by ultrasonic waves. Copyright © 2011 by ASME.

DOI： 10.1115/imece2011-63414

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84869197867&origin=inward

Effects of high shear rate on thrombus formation process on pipe orifice flows 査読有り国際誌

Tamagawa M.

ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 2 261 - 264 2011年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes visualization of thrombus formation process on orifice flows by laser sheet beam. The aim is to investigate the effects of high shear stress or shear rate on the thrombus formation or thrombus formation rate. In addition, the experimental results are compared with the CFD results. As a result, it was found that the high shear rate region of the flow has large effects of the thrombus formation and prediction method based on CFD can be used. Copyright © 2011 by ASME.

DOI： 10.1115/imece2011-62986

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84869156098&origin=inward

Simulation of thrombus formation process using Lattice Boltzmann Method with consideration of adhesion force to wall 査読有り国際誌

玉川　雅章

Proceedings of the ASME 2010 International Mechanical Engineering Congress & Exposition(IMECE2010) 9 40859 - 40859 2010年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

2010年04月 - 2010年04月

Recently artificial organs, especially rotary blood pumps, have been developed in the worldwide, but in this development, thrombus occurs in the pumps. In general, the main physical factors of thrombus formation are considered to be shear rate, wall properties for blood's adhesion. But, there are no proper CFD codes for predicting thrombus formations using physical parameters in shear flows. In this paper, new model for predicting thrombus formation by considering aggregation and adhesion force to the wall by lattice Boltzmann method is proposed, and the trend of thrombus's adhesion to the wall can be simulated more adequately than that of previous one. Copyright © 2010 by ASME.

DOI： 10.1115/IMECE2010-40859

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84881418598&origin=inward

Analysis of a Bubble Deformation Process in a Microcapsule for Developing Drug Delivery Systems using Underwater Shock Waves 査読有り国際誌

玉川　雅章

Proc. of ASME 2010 3rd Joint US-European Fluids Engineering Summer Meeting and 8th InternationalConference on Nanochannels, Microchannels, and Minichannels(FEDSM2010-ICNMM2010) 1 ( PARTS A, B AND C ) 31242 - 31242 2010年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

2010年04月 - 2010年04月

This paper describes development of microcapsule using underwater shock waves, especially (1) the trial of making smaller microcapsules including a bubble for shock wave drug delivery systems, and analysis of a bubble deformation process to have higher efficiency of disintegration by shock wave, and (2) the effects of gradient of cytokine concentration on neutrophile motion in liquid by observing the concentration transport process with adding cytokine for developing drug delivery systems Copyright © 2010 by ASME.

DOI： 10.1115/FEDSM-ICNMM2010-31242

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=80054988039&origin=inward

Visualization of thrombus formation process on pipe orifice flows by laser sheet 査読有り国際誌

玉川　雅章

Proceedings of the ASME 2010 International Mechanical Engineering Congress & Exposition(IMECE2010) 2 38607 - 38607 2010年04月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

2010年04月 - 2010年04月

This paper describes visualization of thrombus formation process on orifice flows by laser sheet beam. The aim is to investigate the effects of shear stress or shear rate on the thrombus formation or thrombus formation rate. In this investigation, by visualization of the thrombus formation in blood plasma flow, it was found that the high shear rate region of the flow has large effects of the thrombus formation. Copyright © 2010 by ASME.

DOI： 10.1115/IMECE2010-38607

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84881409723&origin=inward

Prediction method of thrombus formation process in separation and reattachment blood flow using lattice Boltzmann method 査読有り

Tamagawa M.

ASME International Mechanical Engineering Congress and Exposition, Proceedings 13 121 - 123 2010年01月

記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow. Copyright © 2010 by ASME.

DOI： 10.1115/IMECE2009-10718

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77954295358&origin=inward

CFD study of thrombus formation on shear blood flows by using modified lattice Boltzmann method and thrombus observation 査読有り国際誌

Tamagawa M.

Proceedings of the ASME Summer Bioengineering Conference, SBC2008 ( PART B ) 983 - 984 2009年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow. Copyright © 2008 by ASME.

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77952639403&origin=inward

Elucidation of Driving Force of Neutrophile in Liquid by Cytokine Concentration Gradient 査読有り国際誌

Tamagawa M., Matsumura K.

IFMBE Proceedings 23 882 - 883 2009年12月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes the effects of gradient of cytokine concentration on chemotaxis of neutrophile by observing the motion in liquid with adding cytokine concentration. The aim of this investigation is to control of neutrophile motion in liquid by concentration gradient for drug delivery systems. © International Federation of Medical and Biological Engineering 2009.

DOI： 10.1007/978-3-540-92841-6_217

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84891912900&origin=inward

CFD based prediction method of thrombus formation in shear flow and its validation 査読有り国際誌

Tamagawa M., Nagahama S.

ASME International Mechanical Engineering Congress and Exposition, Proceedings 2 469 - 470 2009年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow. Copyright © 2008 by ASME.

DOI： 10.1115/IMECE2008-67265

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70049087123&origin=inward

Effects of shock waves on acceleration of cell growth rate by shock tube 査読有り国際誌

Tamagawa M., Ishimatsu N.

ASME International Mechanical Engineering Congress and Exposition, Proceedings 2 655 - 656 2009年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes effects of shock waves on cells to certificate the angiogenesis by shock wave (pressure wave) in the clinical application such as ESW (Extracorporeal Shock Wave). Especially, to investigate the effects of shock waves on the endothelial cells in vitro, the cells worked by plane shock waves using shock tube apparatus are observed and measured in the microscope. The peak pressure working on the endothelial cells at the test case is 0.4 MPa. After working shock waves on suspended cells, growth rate (area per one cell and population of cells) are measured by image processing. It is found that the growth rate of the shock-worked cells from 0 to 4h is clearly high compared with control one. It is concluded that once shock waves worked, the cells have capacity to increase growth rate in vitro. This preliminary result will be applied to fundamental investigations about shock wave stimulus on several kinds of cells in future. Copyright © 2008 by ASME.

DOI： 10.1115/IMECE2008-68216

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=70049112104&origin=inward

Development of microcapsules including a gas bubble for shock wave based drug delivery 査読有り国際誌

Tamagawa M., Ishimatsu N.

2008 Proceedings of the ASME Fluids Engineering Division Summer Conference, FEDSM 2008 2 105 - 106 2009年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes the trial of making microcapsules including a bubble for shock wave drug delivery systems, evaluation of their mechanical properties and development of new driving mechanics of the microcapsules. Copyright © 2008 by ASME.

DOI： 10.1115/FEDSM2008-55320

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=69949163676&origin=inward

Fundamental investigations of driving force of a neutrophile in liquid using concentration marangoni effect for developing microcapsules in drug delivery systems 査読有り国際誌

Tamagawa M.

2008 Proceedings of the ASME Fluids Engineering Division Summer Conference, FEDSM 2008 2 103 - 104 2009年09月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes the effects of gradient of cytokine concentration on chemotaxis of neutrophile by observing the motion in liquid with adding cytokine concentration. The aim of this investigation is to control of neutrophile motion in liquid by concentration gradient for drug delivery systems. Copyright © 2008 by ASME.

DOI： 10.1115/FEDSM2008-55319

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=69949138606&origin=inward

Simulation of Thrombus Formation in Shear Flows Using Lattice Boltzmann method 査読有り

Masaaki TAMAGAWA,Hiroaki KANEDA,Sho NAGAHAMA

Artificial Organs printing - printing 2009年08月

Simulation of thrombus formation in shear flows using lattice boltzmann method 査読有り国際誌

Tamagawa M., Kaneda H., Hiramoto M., Nagahama S.

Artificial Organs 33 ( 8 ) 604 - 610 2009年08月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

This article describes the prediction of index of thrombus formation in shear blood flow by computational fluid dynamics with the Lattice Boltzmann Method (LBM), applying to backward-facing step flow, which is a simple model of shear flow in the rotary blood pumps and complicated geometry of medical fluid devices. Assuming that the blood flow is a multiphase flow composed of blood plasma and activated fibrinogen, the effects of surface tension and adhesion force to the wall were added to the LBM computational model. It was found that the thrombus formation in the backward-facing step flow occurred just after the reattachment point and behind the step. These results corresponded to our observation results of thrombus formation. For the thrombus formation in every case of blood flow to be predicted, effects of threshold level of physical parameters such as shear rate and adhesion force (effective distance from the wall) were estimated. Moreover, it was also found that the predicted adhesion point on the wall agrees with the visualization of thrombus formation by predicting proper thresholds. © 2009, International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

DOI： 10.1111/j.1525-1594.2009.00782.x

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=68549086963&origin=inward

Driving force of a neutrophile in liquid using concentration Marangorni effect for developing microcapsule for Drug Delivery Systems 査読有り

Tamagawa and K. Matsumura

IFMBE Proceedings 25/IV (Proc of Medical Physics and Biomedical Engineering, World Congress 2009) 200 - 201 2009年04月

Visualization of thrombus formation and CFD based prediction on shear flows 査読有り

Tamagawa and R. Toyao

IFMBE Proceedings 25/IV (Proc of Medical Physics and Biomedical Engineering, World Congress 2009) 1099 - 1100 2009年04月

Driving force of a neutrophile in liquid using concentration Marangorni effect for developing microcapsule for Drug Delivery Systems 査読有り国際誌

Tamagawa M., Matsumura K.

IFMBE Proceedings 25 ( 8 ) 200 - 201 2009年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes the effects of gradient of cytokine concentration on chemotaxis of neutrophile by observing the motion in liquid with adding cytokine concentration. The aim of this investigation is to control of microcapsule motion in liquid by concentration gradient for drug delivery systems. © 2009 Springer-Verlag.

DOI： 10.1007/978-3-642-03887-7_55

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77949892312&origin=inward

Visualization of thrombus formation and CFD based prediction on shear flows 査読有り国際誌

Tamagawa M., Toyao R.

IFMBE Proceedings 25 ( 4 ) 1099 - 1100 2009年01月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

This paper describes development of the prediction method of thrombus formation by Computational Fluid Dynamics (CFD) on pipe orifice shear flows. These shear flows are typical models of the flow in the rotary blood pump. In this investigation, the thrombus formation in blood plasma flow is visualized, and normal FDM (Finite Difference Method) and modified lattice Boltzmann method are used to predict the backward forwarding step flow, that is simple model of the orifice flow.

DOI： 10.1007/978-3-642-03882-2_292

その他リンク： https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=77950182748&origin=inward

衝撃波を用いた細胞への力学的刺激時の応力波解析査読有り

石松憲和，山野井一郎，玉川雅章，高須登実男

生体医工学 46 ( 2 ) printing - printing 2008年04月

CFD based prediction method of thrombus formation in shear flow and its validation 査読有り

Masaaki TAMAGAWA,Sho NAGAHAMA

Proceedings of IMECE2008 (2008 ASME International Mechanical Engineering Congress and Exposition) 67265 - 67265 2008年04月

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